# GeDiPNet Shared-Gene Disease Pairs -- generated 2026-10-12 03:14:18
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test (P(X>=k)), Benjamini-Hochberg FDR-corrected across all tested pairs. Corroborated Shared Genes: count of shared genes backed by >=2 distinct disease_gdp.main_source values combined across both diseases (e.g. GWAS-backed for one, ClinVar-backed for the other still counts); Shared Gene Names lists each gene's own source count in parentheses. Overlap Coefficient: shared genes / MIN(each disease's own total gene count) -- complements the Jaccard-based Similarity Score by showing how much of the SMALLER disease's entire known gene-set is covered by this pair, which Jaccard (dividing by the union) can understate. Shared Cluster: cluster id if both diseases fall in the same label-propagation cluster (scripts/build_disease_clusters.php), blank otherwise. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-12 03:00:13. Filters applied: disease name contains "Sebaceous gland neoplasms" (5 matching pairs).
Disease A	Disease B	Shared Genes	Corroborated Shared Genes	Shared Gene Names	Similarity Score	Overlap Coefficient	P-value	FDR Q-value	Shared Cluster
Ectrodactyly	Sebaceous gland neoplasms	1	1	LEF1 (2)	0.09091	1.00000	6.494e-4	1.241e-3	
Potassium deficiency	Sebaceous gland neoplasms	1	1	LEF1 (2)	0.05263	1.00000	1.169e-3	1.895e-3	
Ectodermal dysplasia	Sebaceous gland neoplasms	1	1	LEF1 (2)	0.03030	1.00000	2.078e-3	2.969e-3	
Lymphocytic b-cell leukemia	Sebaceous gland neoplasms	1	0	LEF1 (1)	0.02857	1.00000	2.208e-3	3.113e-3	
Lymphocytic leukemia	Sebaceous gland neoplasms	1	1	LEF1 (2)	0.00862	1.00000	7.469e-3	8.758e-3