# GeDiPNet Shared-Gene Disease Pairs -- generated 2026-10-20 06:37:13
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test (P(X>=k)), Benjamini-Hochberg FDR-corrected across all tested pairs. Corroborated Shared Genes: count of shared genes backed by >=2 distinct disease_gdp.main_source values combined across both diseases (e.g. GWAS-backed for one, ClinVar-backed for the other still counts); Shared Gene Names lists each gene's own source count in parentheses. Overlap Coefficient: shared genes / MIN(each disease's own total gene count) -- complements the Jaccard-based Similarity Score by showing how much of the SMALLER disease's entire known gene-set is covered by this pair, which Jaccard (dividing by the union) can understate. Shared Cluster: cluster id if both diseases fall in the same label-propagation cluster (scripts/build_disease_clusters.php), blank otherwise. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-20 03:00:20. Filters applied: disease name contains "Intellectual disability, epilepsy and autism" (5 matching pairs).
Disease A	Disease B	Shared Genes	Corroborated Shared Genes	Shared Gene Names	Similarity Score	Overlap Coefficient	P-value	FDR Q-value	Shared Cluster
Intellectual developmental disorder seizures language	Intellectual disability, epilepsy and autism	1	1	SETD1B (4)	0.50000	1.00000	6.457e-5	1.985e-4	
Intellectual disability, epilepsy and autism	Monoclonal b-cell lymphocytosis	1	0	SETD1B (1)	0.08333	1.00000	7.102e-4	1.174e-3	
Intellectual disability, epilepsy and autism	Salivary gland mucoepidermoid carcinoma	1	0	SETD1B (1)	0.02941	1.00000	2.131e-3	2.847e-3	
Intellectual disability, epilepsy and autism	Thymoma	1	0	SETD1B (1)	0.02222	1.00000	2.841e-3	3.633e-3	
Intellectual disability, epilepsy and autism	Lung sarcomatoid carcinoma	1	0	SETD1B (1)	0.01695	1.00000	3.745e-3	4.636e-3