# GeDiPNet Shared-Gene Disease Pairs -- generated 2026-10-10 22:25:15
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test (P(X>=k)), Benjamini-Hochberg FDR-corrected across all tested pairs. Corroborated Shared Genes: count of shared genes backed by >=2 distinct disease_gdp.main_source values combined across both diseases (e.g. GWAS-backed for one, ClinVar-backed for the other still counts); Shared Gene Names lists each gene's own source count in parentheses. Overlap Coefficient: shared genes / MIN(each disease's own total gene count) -- complements the Jaccard-based Similarity Score by showing how much of the SMALLER disease's entire known gene-set is covered by this pair, which Jaccard (dividing by the union) can understate. Shared Cluster: cluster id if both diseases fall in the same label-propagation cluster (scripts/build_disease_clusters.php), blank otherwise. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-11 03:00:14. Filters applied: disease name contains "Discoid lupus erythematosus" (5 matching pairs).
Disease A	Disease B	Shared Genes	Corroborated Shared Genes	Shared Gene Names	Similarity Score	Overlap Coefficient	P-value	FDR Q-value	Shared Cluster
Discoid lupus erythematosus	Urologic neoplasms	1	1	OGG1 (2)	0.10000	0.50000	1.039e-3	1.739e-3	
Developmental coordination disorder	Discoid lupus erythematosus	1	0	OGG1 (1)	0.07143	0.50000	1.558e-3	2.376e-3	
Discoid lupus erythematosus	Motor skills disorder	1	1	OGG1 (2)	0.06667	0.50000	1.688e-3	2.531e-3	
Discoid lupus erythematosus	Senile cataract	1	0	OGG1 (1)	0.06667	0.50000	1.688e-3	2.531e-3	
Discoid lupus erythematosus	Hyperplasia	1	1	OGG1 (2)	0.03030	0.50000	4.023e-3	5.086e-3