# GeDiPNet Shared-Gene Disease Pairs -- generated 2026-10-11 17:49:39
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test (P(X>=k)), Benjamini-Hochberg FDR-corrected across all tested pairs. Corroborated Shared Genes: count of shared genes backed by >=2 distinct disease_gdp.main_source values combined across both diseases (e.g. GWAS-backed for one, ClinVar-backed for the other still counts); Shared Gene Names lists each gene's own source count in parentheses. Overlap Coefficient: shared genes / MIN(each disease's own total gene count) -- complements the Jaccard-based Similarity Score by showing how much of the SMALLER disease's entire known gene-set is covered by this pair, which Jaccard (dividing by the union) can understate. Shared Cluster: cluster id if both diseases fall in the same label-propagation cluster (scripts/build_disease_clusters.php), blank otherwise. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-11 03:00:14. Filters applied: disease name contains "Coronary thrombosis" (7 matching pairs).
Disease A	Disease B	Shared Genes	Corroborated Shared Genes	Shared Gene Names	Similarity Score	Overlap Coefficient	P-value	FDR Q-value	Shared Cluster
Coronary thrombosis	Von willebrand disorder	2	1	PLAT (2), GP6 (1)	0.10000	0.22222	1.998e-5	9.476e-5	
Coronary thrombosis	Platelet disorder	2	1	ITGB3 (2), GP6 (1)	0.08333	0.16667	4.322e-5	1.965e-4	
Coronary thrombosis	Intracranial hemorrhage	2	1	SCAPER (1), PLAT (2)	0.08333	0.16667	4.322e-5	1.965e-4	
Coronary thrombosis	Intellectual developmental disorder with retinitis pigmentosa	1	1	SCAPER (5)	0.07692	1.00000	7.793e-4	1.405e-3	
Cardiac tamponade	Coronary thrombosis	1	1	PLAT (2)	0.07692	1.00000	7.793e-4	1.405e-3	
Coronary thrombosis	Glycoprotein vi deficiency	1	0	GP6 (1)	0.07692	1.00000	7.793e-4	1.405e-3	
Coronary thrombosis	platelet-type bleeding disorder 11	1	1	GP6 (2)	0.07692	1.00000	7.793e-4	1.405e-3