# GeDiPNet Shared-Gene Disease Pairs -- generated 2026-10-11 22:28:06
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test (P(X>=k)), Benjamini-Hochberg FDR-corrected across all tested pairs. Corroborated Shared Genes: count of shared genes backed by >=2 distinct disease_gdp.main_source values combined across both diseases (e.g. GWAS-backed for one, ClinVar-backed for the other still counts); Shared Gene Names lists each gene's own source count in parentheses. Overlap Coefficient: shared genes / MIN(each disease's own total gene count) -- complements the Jaccard-based Similarity Score by showing how much of the SMALLER disease's entire known gene-set is covered by this pair, which Jaccard (dividing by the union) can understate. Shared Cluster: cluster id if both diseases fall in the same label-propagation cluster (scripts/build_disease_clusters.php), blank otherwise. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-12 03:00:13. Filters applied: disease name contains "Benign essential blepharospasm" (5 matching pairs).
Disease A	Disease B	Shared Genes	Corroborated Shared Genes	Shared Gene Names	Similarity Score	Overlap Coefficient	P-value	FDR Q-value	Shared Cluster
Benign essential blepharospasm	Blepharospasm	1	1	DRD5 (3)	0.50000	1.00000	6.494e-5	2.331e-4	
Benign essential blepharospasm	Bipolar depression	1	1	DRD5 (2)	0.00943	1.00000	6.819e-3	8.095e-3	
Benign essential blepharospasm	Psychotic disorders	1	1	DRD5 (2)	0.00794	1.00000	8.118e-3	9.424e-3	
Attention deficit hyperactivity disorder	Benign essential blepharospasm	1	1	DRD5 (2)	0.00090	1.00000	7.176e-2	7.308e-2	
Benign essential blepharospasm	Bipolar disorder	1	1	DRD5 (2)	0.00082	1.00000	7.923e-2	8.034e-2