# GeDiPNet Cluster 93 -- Enriched Pathways -- generated 2026-10-07 14:46:40
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Non-integrin membrane-ECM interactions	Reactome	4	COL1A1, COL1A2, PDGFB, COL5A1	24	38	52.68	8.651e-7	4.300e-5
Extracellular matrix organization	Reactome	3	COL1A1, COL1A2, COL5A1	15	38	63.21	1.295e-5	4.165e-4
ECM proteoglycans	Reactome	4	COL1A1, ITGB6, COL1A2, COL5A1	51	38	24.79	1.914e-5	5.780e-4
Collagen degradation	Reactome	4	COL1A1, COL1A2, COL5A1, CTSK	52	38	24.31	2.069e-5	6.151e-4
Crosslinking of collagen fibrils	Reactome	3	COL1A1, COL1A2, LOXL4	18	38	52.68	2.308e-5	6.713e-4
MET activates PTK2 signaling	Reactome	3	COL1A1, COL1A2, COL5A1	30	38	31.61	1.119e-4	2.456e-3
Integrin cell surface interactions	Reactome	4	COL1A1, ITGB6, COL1A2, COL5A1	81	38	15.61	1.190e-4	2.577e-3
Platelet Aggregation (Plug Formation)	Reactome	2	COL1A1, COL1A2	8	38	79.01	2.697e-4	4.941e-3
AGE-RAGE signaling pathway in diabetic complications	KEGG	4	COL1A1, EGR1, TGFB2, COL1A2	101	38	12.52	2.792e-4	5.075e-3
Amoebiasis	KEGG	4	COL1A1, TGFB2, NOS2, COL1A2	103	38	12.27	3.010e-4	5.377e-3
Collagen chain trimerization	Reactome	3	COL1A1, COL1A2, COL5A1	44	38	21.55	3.539e-4	6.101e-3
Interleukin-4 and Interleukin-13 signaling	Reactome	4	TIMP1, HIF1A, NOS2, COL1A2	108	38	11.71	3.607e-4	6.190e-3
Platelet Adhesion to exposed collagen	Reactome	2	COL1A1, COL1A2	11	38	57.46	5.266e-4	8.285e-3
Assembly of collagen fibrils and other multimeric structures	Reactome	3	COL1A1, COL1A2, COL5A1	51	38	18.59	5.480e-4	8.541e-3
GP1b-IX-V activation signalling	Reactome	2	COL1A1, COL1A2	12	38	52.68	6.307e-4	9.561e-3