# GeDiPNet Cluster 92 -- Pairs Within Cluster -- generated 2026-10-07 22:50:38
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:00:12.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Septopreoptic holoprosencephaly	Syntelencephaly	0.93750	15	2.030e-51	1.097e-49
Semilobar holoprosencephaly	Septopreoptic holoprosencephaly	0.78947	15	1.656e-48	8.370e-47
Semilobar holoprosencephaly	Syntelencephaly	0.78947	15	1.656e-48	8.370e-47
Holoprosencephaly	Semilobar holoprosencephaly	0.54839	17	2.178e-48	1.093e-46
Microform holoprosencephaly	Semilobar holoprosencephaly	0.75000	15	2.650e-47	1.307e-45
Microform holoprosencephaly	Septopreoptic holoprosencephaly	0.77778	14	3.747e-45	1.769e-43
Microform holoprosencephaly	Syntelencephaly	0.77778	14	3.747e-45	1.769e-43
Holoprosencephaly	Septopreoptic holoprosencephaly	0.50000	15	1.574e-43	7.175e-42
Holoprosencephaly	Syntelencephaly	0.50000	15	1.574e-43	7.175e-42
Holoprosencephaly	Microform holoprosencephaly	0.48387	15	2.517e-42	1.111e-40
Gastrointestinal stromal tumor	Microform holoprosencephaly	0.08475	5	9.065e-10	8.273e-9
Gastrointestinal stromal tumor	Holoprosencephaly	0.06944	5	2.393e-8	1.862e-7
Gastrointestinal stromal tumor	Syntelencephaly	0.06780	4	1.015e-7	7.124e-7
22q11 deletion syndrome	Septopreoptic holoprosencephaly	0.06250	1	9.742e-4	1.663e-3
neurodevelopmental disorder with nonspecific brain abnormalities and with or without seizures	Septopreoptic holoprosencephaly	0.06250	1	9.742e-4	1.663e-3
neurodevelopmental disorder with nonspecific brain abnormalities and with or without seizures	Syntelencephaly	0.06250	1	9.742e-4	1.663e-3
22q11 deletion syndrome	Syntelencephaly	0.06250	1	9.742e-4	1.663e-3
Microform holoprosencephaly	neurodevelopmental disorder with nonspecific brain abnormalities and with or without seizures	0.05882	1	1.039e-3	1.737e-3
22q11 deletion syndrome	Microform holoprosencephaly	0.05882	1	1.039e-3	1.737e-3
neurodevelopmental disorder with nonspecific brain abnormalities and with or without seizures	Semilobar holoprosencephaly	0.05263	1	1.169e-3	1.894e-3
Holoprosencephaly	holoprosencephaly-hypokinesia-congenital contractures syndrome	0.03333	1	1.883e-3	2.760e-3
Holoprosencephaly	neurodevelopmental disorder with nonspecific brain abnormalities and with or without seizures	0.03333	1	1.883e-3	2.760e-3
ciliary dyskinesia, primary, 46	Gastrointestinal stromal tumor	0.02083	1	3.052e-3	4.025e-3
Congenital heart malformation	Septopreoptic holoprosencephaly	0.05000	1	4.862e-3	5.987e-3
Congenital heart malformation	Syntelencephaly	0.05000	1	4.862e-3	5.987e-3
Congenital heart malformation	Microform holoprosencephaly	0.04762	1	5.185e-3	6.342e-3
Congenital heart malformation	Semilobar holoprosencephaly	0.04348	1	5.832e-3	7.049e-3