# GeDiPNet Cluster 91 -- Enriched Pathways -- generated 2026-10-08 04:59:49
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Defective SLC2A10 causes arterial tortuosity syndrome (ATS)	Reactome	1	SLC2A10	1	36	333.61	2.998e-3	3.114e-2
NGF processing	Reactome	1	PCSK5	4	36	83.40	1.194e-2	7.793e-2
Activation of NIMA Kinases NEK9, NEK6, NEK7	Reactome	1	NEK9	7	36	47.66	2.080e-2	1.083e-1
Suppression of apoptosis	Reactome	1	RNF213	7	36	47.66	2.080e-2	1.083e-1
Focal adhesion	KEGG	3	VAV3, FLNA, LAMA5	203	36	4.93	2.256e-2	1.135e-1
OAS antiviral response	Reactome	1	FLNA	9	36	37.07	2.667e-2	1.247e-1
Assembly of active LPL and LIPC lipase complexes	Reactome	1	PCSK5	11	36	30.33	3.250e-2	1.383e-1
Cell-extracellular matrix interactions	Reactome	1	FLNA	12	36	27.80	3.540e-2	1.450e-1
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Reactome	1	CHRNA7	12	36	27.80	3.540e-2	1.450e-1
GP1b-IX-V activation signalling	Reactome	1	FLNA	12	36	27.80	3.540e-2	1.450e-1
Glucagon signaling pathway	KEGG	2	CREB5, PGAM1	107	36	6.24	4.070e-2	1.560e-1
KSRP (KHSRP) binds and destabilizes mRNA	Reactome	1	EXOSC1	15	36	22.24	4.406e-2	1.629e-1
Cholinergic synapse	KEGG	2	CHRNA7, CREB5	115	36	5.80	4.636e-2	1.678e-1
mRNA decay by 3' to 5' exoribonuclease	Reactome	1	EXOSC1	16	36	20.85	4.693e-2	1.686e-1
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	Reactome	1	EXOSC1	17	36	19.62	4.979e-2	1.742e-1