# GeDiPNet Cluster 90 -- Pairs Within Cluster -- generated 2026-10-07 05:31:00
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:00:12.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Congenital malformation syndromes predominantly affecting facial appearance	Warburg micro syndrome	0.80000	4	4.271e-16	6.895e-15
Apert syndrome	Warburg micro syndrome	0.66667	4	2.135e-15	3.300e-14
Apert syndrome	Congenital malformation syndromes predominantly affecting facial appearance	0.66667	4	2.135e-15	3.300e-14
Cyclocephaly	Warburg micro syndrome	0.50000	4	1.495e-14	2.182e-13
Cryptophthalmos syndrome	Warburg micro syndrome	0.50000	4	1.495e-14	2.182e-13
Congenital malformation syndromes predominantly affecting facial appearance	Cyclocephaly	0.50000	4	1.495e-14	2.182e-13
Congenital malformation syndromes predominantly affecting facial appearance	Cryptophthalmos syndrome	0.50000	4	1.495e-14	2.182e-13
Apert syndrome	Cryptophthalmos syndrome	0.44444	4	7.473e-14	1.033e-12
Apert syndrome	Cyclocephaly	0.44444	4	7.473e-14	1.033e-12
Goldenhar syndrome	Warburg micro syndrome	0.36364	4	8.969e-14	1.230e-12
Congenital malformation syndromes predominantly affecting facial appearance	Goldenhar syndrome	0.36364	4	8.969e-14	1.230e-12
Apert syndrome	Goldenhar syndrome	0.33333	4	4.483e-13	5.927e-12
Cryptophthalmos syndrome	Cyclocephaly	0.36364	4	5.229e-13	6.860e-12
Congenital malformation syndromes predominantly affecting facial appearance	Mobius syndrome	0.25000	4	5.830e-13	7.602e-12
Mobius syndrome	Warburg micro syndrome	0.25000	4	5.830e-13	7.602e-12
Apert syndrome	Mobius syndrome	0.23529	4	2.913e-12	3.535e-11
Cryptophthalmos syndrome	Goldenhar syndrome	0.28571	4	3.136e-12	3.789e-11
Cyclocephaly	Goldenhar syndrome	0.28571	4	3.136e-12	3.789e-11
Cryptophthalmos syndrome	Mobius syndrome	0.21053	4	2.037e-11	2.297e-10
Cyclocephaly	Mobius syndrome	0.21053	4	2.037e-11	2.297e-10
Cataract-intellectual disability-hypogonadism syndrome	Congenital malformation syndromes predominantly affecting facial appearance	0.40000	2	5.062e-8	3.915e-7
Cataract-intellectual disability-hypogonadism syndrome	Warburg micro syndrome	0.40000	2	5.062e-8	3.915e-7
Cryptophthalmos syndrome	Fraser syndrome	0.12000	3	6.537e-8	5.000e-7
Apert syndrome	Cataract-intellectual disability-hypogonadism syndrome	0.33333	2	8.436e-8	6.270e-7
Cataract-intellectual disability-hypogonadism syndrome	Cryptophthalmos syndrome	0.25000	2	1.772e-7	1.249e-6
Cataract-intellectual disability-hypogonadism syndrome	Cyclocephaly	0.25000	2	1.772e-7	1.249e-6
Cataract-intellectual disability-hypogonadism syndrome	Martsolf syndrome	0.18182	2	3.796e-7	2.527e-6
Martsolf syndrome	Warburg micro syndrome	0.15385	2	2.276e-6	1.327e-5
Congenital malformation syndromes predominantly affecting facial appearance	Martsolf syndrome	0.15385	2	2.276e-6	1.327e-5
Apert syndrome	Martsolf syndrome	0.14286	2	3.792e-6	2.123e-5
Cryptophthalmos syndrome	fraser syndrome 3	0.12500	1	4.546e-4	9.545e-4
Fraser syndrome	primary ciliary dyskinesia 20	0.04762	1	1.299e-3	2.044e-3
Fraser syndrome	fraser syndrome 3	0.04762	1	1.299e-3	2.044e-3