# GeDiPNet Cluster 81 -- Pairs Within Cluster -- generated 2026-10-10 12:41:51
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-10 03:00:13.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
hereditary pheochromocytoma-paraganglioma	Pheochromocytoma/paraganglioma syndrome	0.45455	5	1.631e-16	2.581e-15
hereditary pheochromocytoma-paraganglioma	Paraganglioma	0.45455	5	1.631e-16	2.581e-15
Paraganglioma	Pheochromocytoma/paraganglioma syndrome	0.41667	5	4.348e-16	6.630e-15
Carney-stratakis syndrome	hereditary pheochromocytoma-paraganglioma	0.50000	4	1.495e-14	2.062e-13
Carney-stratakis syndrome	Pheochromocytoma/paraganglioma syndrome	0.44444	4	2.990e-14	4.025e-13
Carney-stratakis syndrome	Paraganglioma	0.44444	4	2.990e-14	4.025e-13
hereditary pheochromocytoma-paraganglioma	Pheochromocytoma	0.20000	4	2.716e-11	2.853e-10
Carney complex	Carney-stratakis syndrome	0.33333	3	2.301e-10	2.206e-9
Carney-stratakis syndrome	Cowden disease	0.27273	3	5.521e-10	5.119e-9
Carney complex	hereditary pheochromocytoma-paraganglioma	0.25000	3	2.012e-9	1.759e-8
Carney complex	Paraganglioma	0.23077	3	3.219e-9	2.760e-8
Carney complex	Pheochromocytoma/paraganglioma syndrome	0.23077	3	3.219e-9	2.760e-8
Cowden disease	hereditary pheochromocytoma-paraganglioma	0.21429	3	4.827e-9	4.076e-8
Cowden disease	Pheochromocytoma/paraganglioma syndrome	0.20000	3	7.721e-9	6.395e-8
Cowden disease	Paraganglioma	0.20000	3	7.721e-9	6.395e-8
Carney-stratakis syndrome	Pheochromocytoma	0.10526	2	6.066e-6	3.097e-5
Carney complex	Cowden disease	0.13333	2	6.368e-6	3.242e-5
Paraganglioma	Pheochromocytoma	0.08696	2	2.824e-5	1.310e-4
Pheochromocytoma	Pheochromocytoma/paraganglioma syndrome	0.08696	2	2.824e-5	1.310e-4
Carcinoid syndrome	Intestinal cancer	0.50000	1	6.494e-5	2.331e-4
Carney-stratakis syndrome	Intestinal cancer	0.20000	1	2.598e-4	6.509e-4
Carcinoid syndrome	Carney-stratakis syndrome	0.20000	1	2.598e-4	6.509e-4
hereditary pheochromocytoma-paraganglioma	Intestinal cancer	0.12500	1	4.546e-4	9.726e-4
Carcinoid syndrome	hereditary pheochromocytoma-paraganglioma	0.12500	1	4.546e-4	9.726e-4
hereditary pheochromocytoma-paraganglioma	Polydactyly-macrocephaly syndrome	0.12500	1	4.546e-4	9.726e-4
Intestinal cancer	Paraganglioma	0.11111	1	5.195e-4	1.061e-3
Intestinal cancer	Pheochromocytoma/paraganglioma syndrome	0.11111	1	5.195e-4	1.061e-3
Carcinoid syndrome	Pheochromocytoma/paraganglioma syndrome	0.11111	1	5.195e-4	1.061e-3
Carcinoid syndrome	Paraganglioma	0.11111	1	5.195e-4	1.061e-3
Carney-stratakis syndrome	Skeletal muscle disorder	0.12500	1	1.039e-3	1.739e-3
Aromatic l-amino-acid decarboxylase deficiency	Pheochromocytoma	0.05882	1	1.039e-3	1.739e-3
Pheochromocytoma	Polydactyly-macrocephaly syndrome	0.05882	1	1.039e-3	1.739e-3
Carney complex	Skeletal muscle disorder	0.09091	1	1.817e-3	2.677e-3
hereditary pheochromocytoma-paraganglioma	Skeletal muscle disorder	0.09091	1	1.817e-3	2.677e-3
Paraganglioma	Skeletal muscle disorder	0.08333	1	2.077e-3	2.969e-3