# GeDiPNet Cluster 81 -- Pairs Within Cluster -- generated 2026-10-08 11:36:31
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:00:12.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Rheumatic disease of mitral valve	Rheumatic mitral regurgitation	0.66667	2	8.436e-9	6.837e-8
Mitral valve disease	Rheumatic mitral regurgitation	0.66667	2	8.436e-9	6.837e-8
Mitral valve disease	Rheumatic disease of mitral valve	0.66667	2	8.436e-9	6.837e-8
Carotid artery stenosis	Coronary restenosis	0.12000	3	1.702e-7	1.150e-6
Coronary restenosis	Mitral valve disease	0.13333	2	7.677e-7	4.587e-6
Coronary restenosis	Rheumatic disease of mitral valve	0.13333	2	7.677e-7	4.587e-6
Coronary restenosis	Rheumatic mitral regurgitation	0.13333	2	7.677e-7	4.587e-6
homocystinuria due to methylene tetrahydrofolate reductase deficiency	Microvascular angina	0.50000	1	6.494e-5	2.317e-4
Microvascular angina	Mitral valve disease	0.33333	1	1.299e-4	3.908e-4
renal tubular dysgenesis - ACE	Rheumatic mitral regurgitation	0.33333	1	1.299e-4	3.908e-4
renal tubular dysgenesis - ACE	Rheumatic disease of mitral valve	0.33333	1	1.299e-4	3.908e-4
Mitral valve disease	renal tubular dysgenesis - ACE	0.33333	1	1.299e-4	3.908e-4
Microvascular angina	Rheumatic mitral regurgitation	0.33333	1	1.299e-4	3.908e-4
Microvascular angina	Rheumatic disease of mitral valve	0.33333	1	1.299e-4	3.908e-4
homocystinuria due to methylene tetrahydrofolate reductase deficiency	Rheumatic mitral regurgitation	0.33333	1	1.299e-4	3.908e-4
homocystinuria due to methylene tetrahydrofolate reductase deficiency	Rheumatic disease of mitral valve	0.33333	1	1.299e-4	3.908e-4
homocystinuria due to methylene tetrahydrofolate reductase deficiency	Mitral valve disease	0.33333	1	1.299e-4	3.908e-4
Microvascular angina	Portal vein thrombosis	0.25000	1	1.948e-4	5.325e-4
homocystinuria due to methylene tetrahydrofolate reductase deficiency	Portal vein thrombosis	0.25000	1	1.948e-4	5.325e-4
Congenital plasminogen activator inhibitor deficiency type 1	Portal vein thrombosis	0.25000	1	1.948e-4	5.325e-4
Mitral valve disease	Portal vein thrombosis	0.20000	1	3.896e-4	8.637e-4
Fabry disease	krabbe disease	0.10000	1	5.845e-4	1.154e-3
Fabry disease	renal tubular dysgenesis - ACE	0.10000	1	5.845e-4	1.154e-3
Fabry disease	Mitral valve disease	0.09091	1	1.169e-3	1.894e-3