# GeDiPNet Cluster 80 -- Pairs Within Cluster -- generated 2026-10-07 09:59:13
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:00:12.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Hepatic insufficiency	Hepatomegaly	0.15254	9	7.960e-23	1.810e-21
Hepatic insufficiency	Urethral obstruction	0.12500	4	7.999e-10	7.722e-9
Pancreatic ductal carcinoma	Urethral obstruction	0.07407	4	1.948e-7	1.367e-6
Endocrine system disease	Hepatic insufficiency	0.09091	2	2.754e-5	1.352e-4
combined immunodeficiency due to RELA haploinsufficiency	Mucocutaneous ulceration	0.50000	1	6.494e-5	2.342e-4
Autoinflammatory disease, familial, behcet-like 3	Mucocutaneous ulceration	0.33333	1	1.299e-4	3.898e-4
Autoinflammatory disease, familial, behcet-like 3	combined immunodeficiency due to RELA haploinsufficiency	0.33333	1	1.299e-4	3.898e-4
Hepatic insufficiency	Pancreatic ductal carcinoma	0.05128	2	1.400e-4	4.194e-4
combined immunodeficiency due to RELA haploinsufficiency	Hepatic insufficiency	0.10000	1	5.845e-4	1.135e-3
Hepatic insufficiency	Mucocutaneous ulceration	0.10000	1	5.845e-4	1.135e-3
combined immunodeficiency due to RELA haploinsufficiency	Endocrine system disease	0.06667	1	9.092e-4	1.557e-3
Endocrine system disease	Mucocutaneous ulceration	0.06667	1	9.092e-4	1.557e-3
Endocrine system disease	multiple congenital anomalies-hypotonia-seizures syndrome 1	0.06667	1	9.092e-4	1.557e-3
Endocrine system disease	Prader-willi-like syndrome	0.06667	1	9.092e-4	1.557e-3
Endocrine system disease	syndromic multisystem autoimmune disease due to ITCH deficiency	0.06667	1	9.092e-4	1.557e-3
combined immunodeficiency due to RELA haploinsufficiency	Cystitis	0.06250	1	9.742e-4	1.644e-3
Cystitis	Mucocutaneous ulceration	0.06250	1	9.742e-4	1.644e-3
Autoinflammatory disease, familial, behcet-like 3	Hepatic insufficiency	0.09091	1	1.169e-3	1.876e-3
Aminoaciduria	Urethral obstruction	0.03704	1	1.689e-3	2.514e-3
Autoinflammatory disease, familial, behcet-like 3	Endocrine system disease	0.06250	1	1.818e-3	2.662e-3
Autoinflammatory disease, familial, behcet-like 3	Cystitis	0.05882	1	1.947e-3	2.813e-3