# GeDiPNet Cluster 75 -- Enriched GO Terms (Biological Process) -- generated 2026-10-08 23:34:44
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-09 03:23:08.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
immune response	GO:0006955	164	CCL2, CCL20, CCL21, CCR6, CD244, CD28, CTLA4, CXCR1, CXCR2, ETS1, FAS, HLA-B	543	1919	2.94	4.757e-39	4.414e-35
inflammatory response	GO:0006954	136	CCL2, CCL20, CCL21, CD40, CXCR2, IL17A, IL18R1, IL18RAP, IL1R1, IL23R, IL27, IL2RA	467	1919	2.84	1.194e-30	7.018e-27
response to lipopolysaccharide	GO:0032496	61	CD6, CSF2RB, CYP1A1, IL10, IL12RB2, IL23R, IRAK1, LITAF, MAPK3, NOS2, NOTCH1, PTPN22	161	1919	3.69	1.100e-20	1.949e-17
cellular response to lipopolysaccharide	GO:0071222	62	CCL2, CD40, IL10, IL12B, IL6, IRAK1, IRGM, JAK2, LITAF, NFKB1, NOD2, NOS2	187	1919	3.23	1.248e-17	1.371e-14
cytokine-mediated signaling pathway	GO:0019221	53	CCL2, CSF2RB, IFNGR2, IFNLR1, IL12RB2, IL1R1, IL1R2, IL23R, IL6, IL6R, IL7R, IRAK1	145	1919	3.56	2.361e-17	2.448e-14
positive regulation of transcription by RNA polymerase II	GO:0045944	213	ACTR2, AHR, ASCL2, CD28, CD40, CREM, CYTL1, EOMES, ETS1, GRHL3, HHEX, IGF2	1208	1919	1.72	5.166e-16	4.347e-13
cell surface receptor signaling pathway via JAK-STAT	GO:0007259	33	CCL2, CD40, CSF2RB, IL12B, IL15RA, IL23R, IL6, IL6R, JAK2, STAT3, TNFRSF1A, TYK2	67	1919	4.80	7.981e-16	6.352e-13
positive regulation of type II interferon production	GO:0032729	35	CD226, CD244, IL12B, IL12RB2, IL18R1, IL1R1, IL2, IL21, IL23R, IL27, JAK2, PTPN22	77	1919	4.43	2.502e-15	1.815e-12
peptide antigen assembly with MHC class II protein complex	GO:0002503	15	HLA-DQA1, HLA-DQB1, HLA-DRB1, B2M, HLA-DOB, HLA-DQB2, HLA-DPA1, HLA-DRA, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DQA2	16	1919	9.13	2.052e-14	1.276e-11
positive regulation of T cell proliferation	GO:0042102	31	CD28, CD6, CORO1A, IL12B, IL2, IL21, IL23R, IL2RA, IL6, JAK2, NR5A2, TYK2	67	1919	4.51	5.341e-14	3.118e-11
positive regulation of T cell activation	GO:0050870	25	CCL2, CD28, CORO1A, HLA-DQA1, HLA-DQB1, HLA-DRB1, NR5A2, PRKCQ, B2M, CCDC88B, CD3E, HLA-DOB	45	1919	5.41	6.877e-14	3.911e-11
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	GO:0002504	14	HLA-DQA1, HLA-DQB1, HLA-DRB1, HLA-DOB, HLA-DQB2, HLA-DPA1, HLA-DRA, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DQA2, HLA-DRB5	15	1919	9.09	1.886e-13	9.824e-11
positive regulation of canonical NF-kappaB signal transduction	GO:0043123	63	CARD9, CCL21, CD40, HLA-DRB1, IL1R1, INAVA, IRAK1, LITAF, LTBR, LURAP1L, NDFIP1, NOD2	232	1919	2.64	2.661e-13	1.352e-10
antigen processing and presentation	GO:0019882	25	HLA-B, HLA-DQA1, HLA-DQB1, HLA-DRB1, HLA-DOB, HLA-DQB2, HFE, HLA-DPA1, HLA-DRA, PSMB8, HLA-C, HLA-DMA	48	1919	5.07	4.939e-13	2.366e-10
B cell differentiation	GO:0030183	32	HHEX, IL10, NKX2-3, PTPN2, AICDA, CD40LG, IL4, BCL6, VCAM1, FOSL2, IKZF3, ITGA4	80	1919	3.90	2.881e-12	1.192e-9