# GeDiPNet Cluster 7 -- Top Shared Genes -- generated 2026-10-07 06:31:37
# Curated genes (disease_gdp) linked to 2 or more of this cluster's member diseases, most widely shared first. Data as of: 2026-10-07 03:15:01.
Gene	Member Diseases Linked	Cluster Size	Linked Diseases
CNGB3	8	35	Cone dystrophy; Cone-rod dystrophy; Leber congenital amaurosis; Macular dystrophy; Nystagmus; Optic atrophy; Retinitis pigmentosa; Stargardt disease
ABCA4	7	35	Cone dystrophy; Cone-rod dystrophy; Leber congenital amaurosis; Macular dystrophy; Optic atrophy; Retinitis pigmentosa; Stargardt disease
CDHR1	7	35	Cone dystrophy; Cone-rod dystrophy; Leber congenital amaurosis; Macular dystrophy; Optic atrophy; Retinitis pigmentosa; retinitis pigmentosa 65
CRB1	7	35	Cone dystrophy; Cone-rod dystrophy; Leber congenital amaurosis; Macular dystrophy; Optic atrophy; Retinitis pigmentosa; Stargardt disease
CRX	7	35	Cone-rod dystrophy; cone-rod dystrophy 2; Leber congenital amaurosis; Macular dystrophy; Retinal degeneration; Retinitis pigmentosa; Stargardt disease
GUCY2D	7	35	Cone dystrophy; Cone-rod dystrophy; Leber congenital amaurosis; Macular dystrophy; Nystagmus; Optic atrophy; Retinitis pigmentosa
NMNAT1	7	35	Cone dystrophy; Cone-rod dystrophy; Leber congenital amaurosis; Nystagmus; Optic atrophy; Retinal degeneration; Retinitis pigmentosa
PRPH2	7	35	Cone dystrophy; Cone-rod dystrophy; Leber congenital amaurosis; Macular dystrophy; Optic atrophy; Retinitis pigmentosa; Stargardt disease
RDH12	7	35	Cone-rod dystrophy; Leber congenital amaurosis; Macular dystrophy; Optic atrophy; Retinal degeneration; Retinitis pigmentosa; Stargardt disease
RHO	7	35	Cone dystrophy; Cone-rod dystrophy; Nystagmus; Optic atrophy; Retinal degeneration; Retinitis pigmentosa; Stargardt disease
RPGR	7	35	Cone dystrophy; Cone-rod dystrophy; Leber congenital amaurosis; Macular dystrophy; Optic atrophy; Retinal degeneration; Retinitis pigmentosa
CERKL	6	35	CERKL-related retinopathy; Cone dystrophy; Cone-rod dystrophy; Macular dystrophy; Retinitis pigmentosa; Stargardt disease
GPHN	6	35	Cone-rod dystrophy; Leber congenital amaurosis; Macular dystrophy; Optic atrophy; Retinitis pigmentosa; Stargardt disease
KCNV2	6	35	Cone dystrophy; Cone-rod dystrophy; Nystagmus; Optic atrophy; Retinitis pigmentosa; Stargardt disease
PDE6B	6	35	Cone dystrophy; Cone-rod dystrophy; Leber congenital amaurosis; Macular dystrophy; Retinal degeneration; Retinitis pigmentosa
PROM1	6	35	Cone-rod dystrophy; Leber congenital amaurosis; Macular dystrophy; Optic atrophy; Retinitis pigmentosa; Stargardt disease
RPE65	6	35	Cone-rod dystrophy; Leber congenital amaurosis; Nystagmus; Retinal degeneration; Retinitis pigmentosa; Stargardt disease
RPGRIP1	6	35	Cone dystrophy; Cone-rod dystrophy; Leber congenital amaurosis; Nystagmus; Optic atrophy; Retinitis pigmentosa
USH2A	6	35	Cone dystrophy; Cone-rod dystrophy; Leber congenital amaurosis; Macular dystrophy; Optic atrophy; Retinitis pigmentosa
CACNA1F	5	35	Cone dystrophy; Cone-rod dystrophy; Macular dystrophy; Optic atrophy; Retinitis pigmentosa
CEP290	5	35	Cone-rod dystrophy; Leber congenital amaurosis; Nystagmus; Optic atrophy; Retinitis pigmentosa
CNGA1	5	35	CNGA1-related retinopathy; Cone-rod dystrophy; Macular dystrophy; Optic atrophy; Retinitis pigmentosa
CNGA3	5	35	Cone dystrophy; Cone-rod dystrophy; Macular dystrophy; Optic atrophy; Retinitis pigmentosa
EYS	5	35	Cone-rod dystrophy; Macular dystrophy; Optic atrophy; Retinitis pigmentosa; Stargardt disease
MFSD8	5	35	Cone-rod dystrophy; Macular dystrophy; Optic atrophy; Retinitis pigmentosa; Stargardt disease
OTX2	5	35	Leber congenital amaurosis; Macular dystrophy; Nystagmus; Optic atrophy; Retinitis pigmentosa
PCARE	5	35	Cone-rod dystrophy; Optic atrophy; PCARE-related retinopathy; Retinitis pigmentosa; Stargardt disease
RAB28	5	35	Cone dystrophy; Cone-rod dystrophy; Optic atrophy; RAB28-related retinopathy; Retinitis pigmentosa
ABHD12	4	35	Cone dystrophy; Optic atrophy; PHARC syndrome; Retinitis pigmentosa
AHI1	4	35	Leber congenital amaurosis; Optic atrophy; Retinal degeneration; Retinitis pigmentosa
ALMS1	4	35	Cone-rod dystrophy; Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
ATF6	4	35	Cone-rod dystrophy; Macular dystrophy; Nystagmus; Retinitis pigmentosa
CABP4	4	35	Cone dystrophy; Cone-rod dystrophy; Optic atrophy; Retinitis pigmentosa
CACNA2D4	4	35	Cone dystrophy; Cone-rod dystrophy; Optic atrophy; Retinitis pigmentosa
CFAP410	4	35	Cone dystrophy; Cone-rod dystrophy; Leber congenital amaurosis; Retinitis pigmentosa
GUCA1A	4	35	Cone dystrophy; Cone-rod dystrophy; Macular dystrophy; Retinitis pigmentosa
GUCA1ANB-GUCA1A	4	35	Cone dystrophy; Cone-rod dystrophy; Macular dystrophy; Retinitis pigmentosa
GUCA1B	4	35	Cone dystrophy; Cone-rod dystrophy; Leber congenital amaurosis; Retinitis pigmentosa
LCA5	4	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa; Stargardt disease
MKS1	4	35	Leber congenital amaurosis; Nystagmus; Optic atrophy; Retinitis pigmentosa
NR2E3	4	35	Cone-rod dystrophy; Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
OPA1	4	35	Cone-rod dystrophy; Optic atrophy; Retinitis pigmentosa; Stargardt disease
PANK2	4	35	Cone-rod dystrophy; Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
PDE6C	4	35	Cone dystrophy; Cone-rod dystrophy; Optic atrophy; Retinitis pigmentosa
RP2	4	35	Cone-rod dystrophy; Leber congenital amaurosis; Macular dystrophy; Retinitis pigmentosa
RPGRIP1L	4	35	Leber congenital amaurosis; Optic atrophy; Retinal degeneration; Retinitis pigmentosa
SCLT1	4	35	Cone-rod dystrophy; Nystagmus; Optic atrophy; Retinitis pigmentosa
SPATA7	4	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa; Stargardt disease
TULP1	4	35	Leber congenital amaurosis; leber congenital amaurosis 15; Retinitis pigmentosa; Stargardt disease
WDR19	4	35	Cone dystrophy; Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
AIPL1	3	35	Cone-rod dystrophy; Leber congenital amaurosis; Retinitis pigmentosa
ARL6	3	35	Cone-rod dystrophy; Optic atrophy; Retinitis pigmentosa
BBS5	3	35	BBS5-related ciliopathy; Cone dystrophy; Retinitis pigmentosa
BEST1	3	35	Macular dystrophy; Retinitis pigmentosa; Stargardt disease
CEP78	3	35	Cone-rod dystrophy; Optic atrophy; Retinitis pigmentosa
CFH	3	35	Optic atrophy; Retinal degeneration; Retinitis pigmentosa
COL18A1	3	35	Macular dystrophy; Nystagmus; Retinitis pigmentosa
COL2A1	3	35	Optic atrophy; Retinitis pigmentosa; Stargardt disease
DTHD1	3	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
EFEMP1	3	35	Macular dystrophy; Optic atrophy; Retinitis pigmentosa
GRM6	3	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
IDH3B	3	35	IDH3B-related retinopathy; Optic atrophy; Retinitis pigmentosa
IFT140	3	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
IMPG1	3	35	Cone-rod dystrophy; Macular dystrophy; Retinitis pigmentosa
IMPG2	3	35	Cone-rod dystrophy; Macular dystrophy; Retinitis pigmentosa
INPP5E	3	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
KIAA1549	3	35	Optic atrophy; Retinitis pigmentosa; retinitis pigmentosa 86
LRAT	3	35	Leber congenital amaurosis; Retinitis pigmentosa; Stargardt disease
LRIT3	3	35	Optic atrophy; Retinitis pigmentosa; Stargardt disease
LRP5	3	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
MERTK	3	35	Cone-rod dystrophy; Optic atrophy; Retinitis pigmentosa
MYO7A	3	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
NBAS	3	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
NPHP3	3	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
NPHP4	3	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
NRL	3	35	Retinal degeneration; Retinitis pigmentosa; retinitis pigmentosa 27
OAT	3	35	Optic atrophy; ornithine aminotransferase deficiency; Retinitis pigmentosa
PCDH15	3	35	Cone dystrophy; Optic atrophy; Retinitis pigmentosa
PITPNM3	3	35	Cone dystrophy; Cone-rod dystrophy; Retinitis pigmentosa
PRPF31	3	35	Leber congenital amaurosis; PRPF31-related retinopathy; Retinitis pigmentosa
RAX2	3	35	Cone-rod dystrophy; Retinal degeneration; Retinitis pigmentosa
RBP3	3	35	Cone-rod dystrophy; Optic atrophy; Retinitis pigmentosa
RGR	3	35	Cone dystrophy; Optic atrophy; Retinitis pigmentosa
RGS9	3	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
RIMS1	3	35	Cone-rod dystrophy; Leber congenital amaurosis; Retinitis pigmentosa
ROM1	3	35	Macular dystrophy; Optic atrophy; Retinitis pigmentosa
RP1	3	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
RP1L1	3	35	Cone dystrophy; Optic atrophy; Retinitis pigmentosa
RP9	3	35	Optic atrophy; Retinitis pigmentosa; retinitis pigmentosa 9
SEMA4A	3	35	Cone-rod dystrophy; Optic atrophy; Retinitis pigmentosa
SLC19A1	3	35	Macular dystrophy; Nystagmus; Retinitis pigmentosa
SNRNP200	3	35	Retinitis pigmentosa; SNRNP200-related dominant retinopathy; Stargardt disease
TMEM126A	3	35	autosomal recessive optic atrophy, OPA7 type; Optic atrophy; Retinitis pigmentosa
TOPORS	3	35	Macular dystrophy; Optic atrophy; Retinitis pigmentosa
TTC8	3	35	Leber congenital amaurosis; Macular dystrophy; Retinitis pigmentosa
TTLL5	3	35	Cone-rod dystrophy; Optic atrophy; Retinitis pigmentosa
TUBB4B	3	35	Leber congenital amaurosis; Retinitis pigmentosa; TUBB4B-related ciliopathy
UNC119	3	35	Cone-rod dystrophy; Macular dystrophy; Retinitis pigmentosa
USP45	3	35	Leber congenital amaurosis; Optic atrophy; Retinitis pigmentosa
ZFYVE26	3	35	Leber congenital amaurosis; Macular dystrophy; Retinitis pigmentosa
ABCC6	2	35	Optic atrophy; Retinitis pigmentosa
ACBD5	2	35	Cone-rod dystrophy; Retinitis pigmentosa
ACO2	2	35	Optic atrophy; Retinitis pigmentosa
ADAM9	2	35	Cone-rod dystrophy; Retinitis pigmentosa
ADAMTS18	2	35	Leber congenital amaurosis; Retinitis pigmentosa
ADGRA3	2	35	Optic atrophy; Retinitis pigmentosa
ADGRV1	2	35	Optic atrophy; Retinitis pigmentosa
AFG3L2	2	35	Optic atrophy; Retinitis pigmentosa
AHR	2	35	Nystagmus; Retinitis pigmentosa
ARHGEF18	2	35	Optic atrophy; Retinitis pigmentosa
ARL3	2	35	Cone dystrophy; Retinitis pigmentosa
BBS10	2	35	Optic atrophy; Retinitis pigmentosa
BBS7	2	35	Optic atrophy; Retinitis pigmentosa
BBS9	2	35	Optic atrophy; Retinitis pigmentosa
C1QTNF5	2	35	Optic atrophy; Retinitis pigmentosa
CC2D2A	2	35	Optic atrophy; Retinitis pigmentosa
CCT2	2	35	Leber congenital amaurosis; Retinitis pigmentosa
CDH23	2	35	Optic atrophy; Retinitis pigmentosa
CDH3	2	35	Macular dystrophy; Retinitis pigmentosa
CEP19	2	35	Optic atrophy; Retinitis pigmentosa
CEP250	2	35	Optic atrophy; Retinitis pigmentosa
CFAP418	2	35	Cone-rod dystrophy; Retinitis pigmentosa
CHST6	2	35	macular corneal dystrophy; Macular dystrophy
CLN3	2	35	Cone-rod dystrophy; Retinitis pigmentosa
CLRN1	2	35	Optic atrophy; Retinitis pigmentosa
CLUAP1	2	35	Leber congenital amaurosis; Retinitis pigmentosa
CNGB1	2	35	Optic atrophy; Retinitis pigmentosa
COL9A1	2	35	Optic atrophy; Retinitis pigmentosa
CSPP1	2	35	Optic atrophy; Retinitis pigmentosa
CTNNA1	2	35	Macular dystrophy; Retinitis pigmentosa
CWC27	2	35	Optic atrophy; Retinitis pigmentosa
CYP4V2	2	35	Optic atrophy; Retinitis pigmentosa
DRAM2	2	35	Cone-rod dystrophy; Retinitis pigmentosa
DYNC2H1	2	35	Optic atrophy; Retinitis pigmentosa
ELOVL1	2	35	Optic atrophy; Retinitis pigmentosa
ELOVL4	2	35	Retinitis pigmentosa; Stargardt disease
ESPN	2	35	Optic atrophy; Retinitis pigmentosa
FAM161A	2	35	Cone-rod dystrophy; Retinitis pigmentosa
FLVCR1	2	35	Retinitis pigmentosa; Stargardt disease
FSCN2	2	35	Leber congenital amaurosis; Retinitis pigmentosa
GDF6	2	35	Leber congenital amaurosis; Retinitis pigmentosa
GIGYF2	2	35	Leber congenital amaurosis; Retinitis pigmentosa
GNAT1	2	35	Retinal degeneration; Retinitis pigmentosa
GNAT2	2	35	Cone dystrophy; Retinitis pigmentosa
GPR179	2	35	Optic atrophy; Retinitis pigmentosa
HARS1	2	35	Nystagmus; Retinitis pigmentosa
HK1	2	35	Macular dystrophy; Retinitis pigmentosa
IFT172	2	35	Optic atrophy; Retinitis pigmentosa
IFT27	2	35	Optic atrophy; Retinitis pigmentosa
IFT74	2	35	Optic atrophy; Retinitis pigmentosa
IFT81	2	35	Cone-rod dystrophy; Retinitis pigmentosa
IMPDH1	2	35	Leber congenital amaurosis; Retinitis pigmentosa
INVS	2	35	Optic atrophy; Retinitis pigmentosa
IQCB1	2	35	Leber congenital amaurosis; Retinitis pigmentosa
ITGA4	2	35	Cone-rod dystrophy; Retinitis pigmentosa
ITM2B	2	35	Optic atrophy; Retinitis pigmentosa
KCNJ13	2	35	Leber congenital amaurosis; Retinitis pigmentosa
KIF11	2	35	Optic atrophy; Retinitis pigmentosa
KIF3B	2	35	Optic atrophy; Retinitis pigmentosa
LAMA1	2	35	Optic atrophy; Retinitis pigmentosa
MAPKAPK3	2	35	Macular dystrophy; Retinitis pigmentosa
MCAT	2	35	Optic atrophy; optic atrophy 15
MFN2	2	35	Optic atrophy; Retinitis pigmentosa
MFRP	2	35	Optic atrophy; Retinitis pigmentosa
MKKS	2	35	Cone dystrophy; Retinitis pigmentosa
MTRFR	2	35	Optic atrophy; Retinitis pigmentosa
NDP	2	35	Nystagmus; Retinitis pigmentosa
NPHP1	2	35	Leber congenital amaurosis; Retinitis pigmentosa
NR2F1	2	35	Optic atrophy; Retinitis pigmentosa
OPA3	2	35	Optic atrophy; Retinitis pigmentosa
PAX2	2	35	Optic atrophy; Retinitis pigmentosa
PAX6	2	35	Nystagmus; Retinitis pigmentosa
PCYT1A	2	35	Leber congenital amaurosis; Retinitis pigmentosa
PDE6A	2	35	Leber congenital amaurosis; Retinitis pigmentosa
PDE6G	2	35	PDE6G-related retinopathy; Retinitis pigmentosa
PDE6H	2	35	Cone dystrophy; Retinitis pigmentosa
PEX1	2	35	Optic atrophy; Retinitis pigmentosa
PGK1	2	35	Optic atrophy; Retinitis pigmentosa
PHYH	2	35	Optic atrophy; Retinitis pigmentosa
PLK4	2	35	Optic atrophy; Retinitis pigmentosa
PNPLA6	2	35	Optic atrophy; Retinitis pigmentosa
POC1B	2	35	Cone-rod dystrophy; Retinitis pigmentosa
POC5	2	35	Optic atrophy; Retinitis pigmentosa
POMGNT1	2	35	Optic atrophy; Retinitis pigmentosa
PRPS1	2	35	Optic atrophy; Retinitis pigmentosa
RD3	2	35	Leber congenital amaurosis; Retinitis pigmentosa
RDH11	2	35	Optic atrophy; Retinitis pigmentosa
RDH5	2	35	Optic atrophy; Retinitis pigmentosa
RDH8	2	35	Corneal degeneration; Stargardt disease
REEP6	2	35	Optic atrophy; Retinitis pigmentosa
RLBP1	2	35	Optic atrophy; Retinitis pigmentosa
RTN4IP1	2	35	Optic atrophy; Retinitis pigmentosa
SAG	2	35	Cone dystrophy; Retinitis pigmentosa
SAMD11	2	35	Optic atrophy; Retinitis pigmentosa
SCAPER	2	35	Optic atrophy; Retinitis pigmentosa
SIX6	2	35	Nystagmus; Retinitis pigmentosa
SLC24A1	2	35	Optic atrophy; Retinitis pigmentosa
SLC25A46	2	35	Optic atrophy; Retinitis pigmentosa
SLC28A1	2	35	Retinal degeneration; Uridine-cytidineuria
SLC38A8	2	35	foveal hypoplasia - optic nerve decussation defect - anterior segment dysgenesis syndrome; Leber congenital amaurosis
SLC4A7	2	35	Cone-rod dystrophy; Retinitis pigmentosa
SLC7A14	2	35	Optic atrophy; Retinitis pigmentosa
SMG8	2	35	Alzahrani-kuwahara syndrome; Retinitis pigmentosa
SOD1	2	35	Retinal degeneration; Retinitis pigmentosa
SRD5A3	2	35	Cone dystrophy; Retinitis pigmentosa
SSBP1	2	35	Cone-rod dystrophy; Optic atrophy
TEAD3	2	35	Leber congenital amaurosis; Retinitis pigmentosa
TMEM67	2	35	Nystagmus; Retinitis pigmentosa
TRNT1	2	35	Optic atrophy; Retinitis pigmentosa
TRPM1	2	35	Optic atrophy; Retinitis pigmentosa
TSPAN1	2	35	Optic atrophy; Retinitis pigmentosa
TSPAN12	2	35	Optic atrophy; Retinitis pigmentosa
TTPA	2	35	Optic atrophy; Retinitis pigmentosa
TUBGCP4	2	35	Optic atrophy; Retinitis pigmentosa
TUBGCP6	2	35	Optic atrophy; Retinitis pigmentosa
UBAP1L	2	35	Cone-rod dystrophy; Retinal degeneration
USH1C	2	35	Optic atrophy; Retinitis pigmentosa
USH1G	2	35	Optic atrophy; Retinitis pigmentosa
WDPCP	2	35	Optic atrophy; Retinitis pigmentosa
WFS1	2	35	Optic atrophy; Retinitis pigmentosa
WHRN	2	35	Optic atrophy; Retinitis pigmentosa
YME1L1	2	35	Optic atrophy; optic atrophy 11
ZNF408	2	35	Optic atrophy; Retinitis pigmentosa
ZNF423	2	35	Optic atrophy; Retinitis pigmentosa
ZNF513	2	35	Optic atrophy; Retinitis pigmentosa