# GeDiPNet Cluster 68 -- Enriched Pathways -- generated 2026-10-08 01:37:58
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Central carbon metabolism in cancer	KEGG	6	HIF1A, MYC, PTEN, SLC2A1, TP53, LDHB	71	27	37.59	9.236e-9	7.884e-7
Endometrial cancer	KEGG	4	CDH1, MYC, PTEN, TP53	59	27	30.16	8.473e-6	2.994e-4
Thyroid cancer	KEGG	3	CDH1, MYC, TP53	37	27	36.07	7.482e-5	1.789e-3
Bladder cancer	KEGG	3	CDH1, MYC, TP53	41	27	32.55	1.020e-4	2.311e-3
Human T-cell leukemia virus 1 infection	KEGG	5	MYC, PTEN, SLC2A1, STAT5A, TP53	224	27	9.93	1.246e-4	2.703e-3
Pathways in cancer	KEGG	7	HIF1A, CDH1, MYC, PTEN, SLC2A1, STAT5A, TP53	533	27	5.84	1.332e-4	2.860e-3
Thyroid hormone signaling pathway	KEGG	4	HIF1A, MYC, SLC2A1, TP53	122	27	14.58	1.484e-4	3.110e-3
Regulation of gene expression by Hypoxia-inducible Factor	Reactome	2	CA9, HIF1A	11	27	80.88	2.644e-4	4.916e-3
Melanoma	KEGG	3	CDH1, PTEN, TP53	73	27	18.28	5.675e-4	8.962e-3
Chronic myeloid leukemia	KEGG	3	MYC, STAT5A, TP53	77	27	17.33	6.635e-4	1.015e-2
Small cell lung cancer	KEGG	3	MYC, PTEN, TP53	93	27	14.35	1.149e-3	1.544e-2
Ub-specific processing proteases	Reactome	4	HIF1A, MYC, PTEN, TP53	220	27	8.09	1.381e-3	1.776e-2
Human cytomegalovirus infection	KEGG	4	BCAR1, MYC, TP53, GNAO1	226	27	7.87	1.525e-3	1.915e-2
Interleukin-4 and Interleukin-13 signaling	Reactome	3	HIF1A, MYC, TP53	108	27	12.36	1.768e-3	2.129e-2
HIF-1 signaling pathway	KEGG	3	HIF1A, SLC2A1, LDHB	110	27	12.13	1.863e-3	2.212e-2