# GeDiPNet Cluster 65 -- Pairs Within Cluster -- generated 2026-10-07 22:47:00
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:00:12.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Chloracne	Thalassemia	0.14706	5	3.292e-14	4.437e-13
Alpha thalassemia	Hemoglobin h disease	0.75000	3	1.644e-12	1.934e-11
Hemoglobin barts fetalis syndrome	Hemoglobin h disease	0.75000	3	1.644e-12	1.934e-11
Hemoglobin m disease	Unstable hemoglobin disease	0.75000	3	1.644e-12	1.934e-11
Alpha thalassemia	Hemoglobin barts fetalis syndrome	0.75000	3	1.644e-12	1.934e-11
Thalassemia	Unstable hemoglobin disease	0.50000	3	1.644e-11	1.781e-10
Hemoglobin m disease	Thalassemia	0.50000	3	1.644e-11	1.781e-10
Methemoglobinemia	Unstable hemoglobin disease	0.42857	3	3.288e-11	3.433e-10
Hemoglobin m disease	Methemoglobinemia	0.42857	3	3.288e-11	3.433e-10
Methemoglobinemia	Thalassemia	0.33333	3	3.287e-10	3.138e-9
erythrocytosis, familial, 7	methemoglobinemia, alpha type	0.66667	2	8.436e-9	6.837e-8
Chloracne	Hemoglobin m disease	0.08824	3	8.968e-9	7.235e-8
Chloracne	Unstable hemoglobin disease	0.08824	3	8.968e-9	7.235e-8
methemoglobinemia, alpha type	Unstable hemoglobin disease	0.50000	2	2.531e-8	1.932e-7
Hemoglobin m disease	methemoglobinemia, alpha type	0.50000	2	2.531e-8	1.932e-7
Hemoglobin h disease	methemoglobinemia, alpha type	0.50000	2	2.531e-8	1.932e-7
Hemoglobin barts fetalis syndrome	methemoglobinemia, alpha type	0.50000	2	2.531e-8	1.932e-7
erythrocytosis, familial, 7	Unstable hemoglobin disease	0.50000	2	2.531e-8	1.932e-7
erythrocytosis, familial, 7	Hemoglobin h disease	0.50000	2	2.531e-8	1.932e-7
Alpha thalassemia	methemoglobinemia, alpha type	0.50000	2	2.531e-8	1.932e-7
Alpha thalassemia	erythrocytosis, familial, 7	0.50000	2	2.531e-8	1.932e-7
erythrocytosis, familial, 7	Hemoglobin barts fetalis syndrome	0.50000	2	2.531e-8	1.932e-7
erythrocytosis, familial, 7	Hemoglobin m disease	0.50000	2	2.531e-8	1.932e-7
Hemoglobin barts fetalis syndrome	Hemoglobin m disease	0.40000	2	7.592e-8	5.427e-7
Hemoglobin h disease	Hemoglobin m disease	0.40000	2	7.592e-8	5.427e-7
Alpha thalassemia	Hemoglobin m disease	0.40000	2	7.592e-8	5.427e-7
erythrocytosis, familial, 7	Thalassemia	0.33333	2	8.436e-8	5.953e-7
methemoglobinemia, alpha type	Thalassemia	0.33333	2	8.436e-8	5.953e-7
erythrocytosis, familial, 7	Methemoglobinemia	0.28571	2	1.265e-7	8.736e-7
Methemoglobinemia	methemoglobinemia, alpha type	0.28571	2	1.265e-7	8.736e-7
Chloracne	Methemoglobinemia	0.08108	3	1.786e-7	1.194e-6
Polycythemia vera	Unstable hemoglobin disease	0.18182	2	9.108e-7	5.383e-6
Hemoglobin m disease	Polycythemia vera	0.18182	2	9.108e-7	5.383e-6
Polycythemia vera	Thalassemia	0.15385	2	3.034e-6	1.636e-5
erythrocytosis, familial, 7	HBA2-related alpha thalassemia spectrum	0.33333	1	1.299e-4	3.908e-4
HBA2-related alpha thalassemia spectrum	methemoglobinemia, alpha type	0.33333	1	1.299e-4	3.908e-4
HBA1-related alpha thalassemia spectrum	methemoglobinemia, alpha type	0.33333	1	1.299e-4	3.908e-4
erythrocytosis, familial, 7	HBA1-related alpha thalassemia spectrum	0.33333	1	1.299e-4	3.908e-4
HBA2-related alpha thalassemia spectrum	Hemoglobin barts fetalis syndrome	0.25000	1	1.948e-4	5.325e-4
HBA2-related alpha thalassemia spectrum	Hemoglobin h disease	0.25000	1	1.948e-4	5.325e-4
Alpha thalassemia	HBA1-related alpha thalassemia spectrum	0.25000	1	1.948e-4	5.325e-4
HBA1-related alpha thalassemia spectrum	Hemoglobin barts fetalis syndrome	0.25000	1	1.948e-4	5.325e-4
Alpha thalassemia	HBA2-related alpha thalassemia spectrum	0.25000	1	1.948e-4	5.325e-4
HBA1-related alpha thalassemia spectrum	Hemoglobin h disease	0.25000	1	1.948e-4	5.325e-4