# GeDiPNet Cluster 64 -- Top Shared Genes -- generated 2026-10-07 13:30:40
# Curated genes (disease_gdp) linked to 2 or more of this cluster's member diseases, most widely shared first. Data as of: 2026-10-07 03:15:01.
Gene	Member Diseases Linked	Cluster Size	Linked Diseases
FBN1	8	14	Aortic dissection; Aortic rupture; Ruptured abdominal aortic aneurysm; Ruptured aortic aneurysm; Ruptured thoracic aortic aneurysm; Shprintzen-goldberg syndrome; Thoracic aortic aneurysm; Thoracoabdominal aortic aneurysm
EFEMP2	7	14	Arterial tortuosity syndrome; cutis laxa, autosomal recessive, type 1B; Ruptured abdominal aortic aneurysm; Ruptured aortic aneurysm; Ruptured thoracic aortic aneurysm; Thoracic aortic aneurysm; Thoracoabdominal aortic aneurysm
MMP9	6	14	Aortic rupture; Ruptured abdominal aortic aneurysm; Ruptured aortic aneurysm; Ruptured thoracic aortic aneurysm; Thoracoabdominal aortic aneurysm; Varicose veins
SMAD3	6	14	Aortic dissection; Cutaneous polyarteritis nodosa; Ruptured abdominal aortic aneurysm; Ruptured aortic aneurysm; Ruptured thoracic aortic aneurysm; Thoracoabdominal aortic aneurysm
AGT	5	14	Aortic dissection; Ruptured abdominal aortic aneurysm; Ruptured aortic aneurysm; Ruptured thoracic aortic aneurysm; Thoracoabdominal aortic aneurysm
ELN	5	14	Ruptured abdominal aortic aneurysm; Ruptured aortic aneurysm; Ruptured thoracic aortic aneurysm; Thoracoabdominal aortic aneurysm; Varicose veins
SKI	5	14	Ruptured abdominal aortic aneurysm; Ruptured aortic aneurysm; Ruptured thoracic aortic aneurysm; Shprintzen-goldberg syndrome; Thoracoabdominal aortic aneurysm
TGFBR2	5	14	Aortic dissection; Ruptured abdominal aortic aneurysm; Ruptured aortic aneurysm; Ruptured thoracic aortic aneurysm; Thoracoabdominal aortic aneurysm
CNTN4	2	14	Atypical femoral fracture; Thoracic aortic aneurysm
IL18R1	2	14	Aortic dissection; Atypical femoral fracture
SLC9A4	2	14	Aortic dissection; Atypical femoral fracture
SMAD6	2	14	Atypical femoral fracture; Thoracic aortic aneurysm