# GeDiPNet Cluster 64 -- Enriched Pathways -- generated 2026-10-08 09:43:08
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Herpes simplex virus 1 infection	KEGG	4	TNF, CCL2, LTA, TAP1	182	14	18.85	4.536e-5	1.197e-3
IL-17 signaling pathway	KEGG	3	TNF, CCL2, MUC5B	94	14	27.38	1.588e-4	3.281e-3
Viral protein interaction with cytokine and cytokine receptor	KEGG	3	TNF, CCL2, LTA	100	14	25.74	1.907e-4	3.811e-3
TNF signaling pathway	KEGG	3	TNF, CCL2, LTA	119	14	21.63	3.188e-4	5.709e-3
Fluid shear stress and atherosclerosis	KEGG	3	TNF, PLAT, CCL2	141	14	18.25	5.244e-4	8.436e-3
Type I diabetes mellitus	KEGG	2	TNF, LTA	44	14	38.99	1.161e-3	1.556e-2
Interleukin-10 signaling	Reactome	2	TNF, CCL2	47	14	36.50	1.324e-3	1.722e-2
Malaria	KEGG	2	TNF, CCL2	50	14	34.31	1.497e-3	1.890e-2
Lipid and atherosclerosis	KEGG	3	TNF, CCL2, SOD2	216	14	11.91	1.804e-3	2.162e-2
Human cytomegalovirus infection	KEGG	3	TNF, CCL2, TAP1	226	14	11.39	2.053e-3	2.372e-2
TNFR2 non-canonical NF-kB pathway	Reactome	2	TNF, LTA	69	14	24.87	2.831e-3	3.003e-2
Antigen processing and presentation	KEGG	2	TNF, TAP1	81	14	21.18	3.879e-3	3.744e-2
Cytokine-cytokine receptor interaction	KEGG	3	TNF, CCL2, LTA	298	14	8.64	4.493e-3	4.138e-2
L1CAM interactions	Reactome	1	L1CAM	4	14	214.46	4.655e-3	4.241e-2
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Reactome	1	IGF2	4	14	214.46	4.655e-3	4.241e-2