# GeDiPNet Cluster 636 -- Pairs Within Cluster -- generated 2026-10-19 23:21:13
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-20 03:00:18.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Leukodystrophy, hypomyelinating with or without oligodontia and/or hypogonadotropic hypogonadism	POLR3B-related disorder	0.50000	1	6.457e-5	1.985e-4
Leukodystrophy, hypomyelinating with or without oligodontia and/or hypogonadotropic hypogonadism	Neurodevelopmental disorder with or without seizures, ataxia, spasticity, and demyelinating neuropathy	0.50000	1	6.457e-5	1.985e-4
Leukodystrophy, hypomyelinating with or without oligodontia and/or hypogonadotropic hypogonadism	Leukodystrophy, hypomyelinating, 8, with or without oligodontia and/or hypogonadotropic hypogonadism	0.50000	1	6.457e-5	1.985e-4
Leukodystrophy, hypomyelinating, 8, with or without oligodontia and/or hypogonadotropic hypogonadism	POLR3B-related disorder	0.50000	1	6.457e-5	1.985e-4
Leukodystrophy, hypomyelinating, 8, with or without oligodontia and/or hypogonadotropic hypogonadism	Neurodevelopmental disorder with or without seizures, ataxia, spasticity, and demyelinating neuropathy	0.50000	1	6.457e-5	1.985e-4
Neurodevelopmental disorder with or without seizures, ataxia, spasticity, and demyelinating neuropathy	POLR3B-related disorder	0.50000	1	6.457e-5	1.985e-4
Leukodystrophy, hypomyelinating with or without oligodontia and/or hypogonadotropic hypogonadism	Tremor-ataxia-central hypomyelination syndrome	0.33333	1	1.291e-4	3.269e-4
Leukodystrophy, hypomyelinating, 8, with or without oligodontia and/or hypogonadotropic hypogonadism	Tremor-ataxia-central hypomyelination syndrome	0.33333	1	1.291e-4	3.269e-4
Neurodevelopmental disorder with or without seizures, ataxia, spasticity, and demyelinating neuropathy	Tremor-ataxia-central hypomyelination syndrome	0.33333	1	1.291e-4	3.269e-4
POLR3B-related disorder	Tremor-ataxia-central hypomyelination syndrome	0.33333	1	1.291e-4	3.269e-4