# GeDiPNet Cluster 63 -- Enriched GO Terms (Biological Process) -- generated 2026-10-07 05:56:15
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:23:06.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
inflammatory response	GO:0006954	55	CCL2, CD14, CEBPB, CXCL10, FOS, IL18R1, IL1A, IL1B, IL1R1, IL1RN, IL6, LY86	467	299	7.36	7.786e-32	4.616e-28
response to lipopolysaccharide	GO:0032496	32	CEBPB, CXCL10, EPO, FOS, IL10, IL12RB2, IL1B, MPO, SOD2, TLR4, TNF, NOS2	161	299	12.42	5.957e-26	2.084e-22
immune response	GO:0006955	51	CCL2, CEBPB, CLEC4E, CSF3, CXCL10, IL10, IL18R1, IL1A, IL1B, IL1R1, IL1RN, IL2	543	299	5.87	7.331e-25	2.269e-21
negative regulation of apoptotic process	GO:0043066	48	BECN1, EPO, GSK3B, HSPA1A, IL10, IL2, IL31RA, IL6, IL7, JUN, MMP9, MPO	524	299	5.73	6.098e-23	1.481e-19
cellular response to lipopolysaccharide	GO:0071222	31	CCL2, CD14, CEBPB, CSF3, CXCL10, IL10, IL1A, IL1B, IL6, MMP9, TICAM2, TLR4	187	299	10.36	1.135e-22	2.683e-19
positive regulation of gene expression	GO:0010628	46	CCL2, CEBPB, FGF2, GSK3B, HSPA1A, IL1A, IL1B, IL6, IL7, PPP3CA, TLR2, TLR4	504	299	5.70	6.182e-22	1.287e-18
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	GO:0051897	32	BECN1, CSF3, FGF2, GSK3B, IL1B, IL1R1, NOX4, TNF, VEGFA, ITGB1, ANGPT1, CAT	217	299	9.22	9.369e-22	1.905e-18
positive regulation of chemokine production	GO:0032722	18	IL1B, IL6, IL7, TLR2, TLR4, TLR9, TNF, EGR1, HIF1A, IL18, AGER, HMOX1	49	299	22.96	2.092e-20	3.641e-17
positive regulation of MAPK cascade	GO:0043410	31	CHRNA7, FGF2, IL1B, IL6, TLR9, TNF, VEGFA, NMNAT1, FGF1, IGF1, MAP2K1, SOD1	224	299	8.65	2.868e-20	4.941e-17
positive regulation of ERK1 and ERK2 cascade	GO:0070374	29	CHRNA7, EPO, FGF2, IL1B, JUN, NOX4, TLR4, TNF, VEGFA, ICAM1, ANGPT1, CCL3	201	299	9.02	1.544e-19	2.338e-16
response to hypoxia	GO:0001666	27	BECN1, CHRNA7, EPO, SOD2, TNF, UCP2, VEGFA, NOS2, CASP3, CASP9, CAT, EGR1	176	299	9.59	5.683e-19	7.878e-16
apoptotic process	GO:0006915	51	BECN1, CD14, EPO, IL1A, IL1B, IRF1, JUN, MMP9, PARP1, TLR2, TNFRSF1A, TNFSF10	747	299	4.27	1.064e-18	1.420e-15
response to xenobiotic stimulus	GO:0009410	30	BECN1, ENO2, FOS, GABRB3, GABRG3, IL10, JUN, SOD2, TNF, RELA, ADD3, CASP3	248	299	7.56	5.764e-18	6.858e-15
positive regulation of interleukin-1 beta production	GO:0032731	18	IL6, TLR4, TNF, RELA, CCL3, EGR1, IL17A, STAT3, AGER, ORM1, PANX1, APP	66	299	17.04	9.714e-18	1.133e-14
positive regulation of inflammatory response	GO:0050729	22	CEBPB, IL1B, IL2, TLR2, TLR4, TLR9, TNF, TNFRSF1A, CCL3, IL17RA, IL18, MDK	122	299	11.27	3.196e-17	3.387e-14