# GeDiPNet Cluster 62 -- Enriched Pathways -- generated 2026-10-09 05:15:13
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-09 03:30:08.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Gap junction assembly	Reactome	2	GJB6, GJB3	18	16	83.40	2.514e-4	4.568e-3
Transport of connexons to the plasma membrane	Reactome	1	GJB2	1	16	750.63	1.332e-3	1.674e-2
5-Phosphoribose 1-diphosphate biosynthesis	Reactome	1	PRPS1	3	16	250.21	3.992e-3	3.753e-2
Formation of the cornified envelope	Reactome	2	LORICRIN, KRT2	130	16	11.55	1.263e-2	8.016e-2
Nef mediated downregulation of MHC class I complex cell surface expression	Reactome	1	AP1B1	10	16	75.06	1.325e-2	8.234e-2
Extracellular matrix organization	Reactome	1	COL4A6	15	16	50.04	1.981e-2	1.044e-1
Anchoring fibril formation	Reactome	1	COL4A6	15	16	50.04	1.981e-2	1.044e-1
Crosslinking of collagen fibrils	Reactome	1	COL4A6	18	16	41.70	2.373e-2	1.157e-1
Non-integrin membrane-ECM interactions	Reactome	1	COL4A6	24	16	31.28	3.152e-2	1.359e-1
Laminin interactions	Reactome	1	COL4A6	28	16	26.81	3.668e-2	1.478e-1
Pentose phosphate pathway	KEGG	1	PRPS1	31	16	24.21	4.053e-2	1.562e-1
Lysosome Vesicle Biogenesis	Reactome	1	AP1B1	35	16	21.45	4.565e-2	1.666e-1
Collagen chain trimerization	Reactome	1	COL4A6	44	16	17.06	5.707e-2	1.879e-1
TBC/RABGAPs	Reactome	1	RAB33A	46	16	16.32	5.959e-2	1.922e-1
Assembly of collagen fibrils and other multimeric structures	Reactome	1	COL4A6	51	16	14.72	6.586e-2	2.026e-1