# GeDiPNet Cluster 609 -- Enriched Pathways -- generated 2026-10-20 00:03:15
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-20 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Presynaptic depolarization and calcium channel opening	Reactome	1	CACNA2D1	12	5	200.17	4.987e-3	3.635e-2
Class B/2 (Secretin family receptors)	Reactome	1	UCN	18	5	133.44	7.473e-3	4.730e-2
Synthesis, secretion, and deacylation of Ghrelin	Reactome	1	UCN	19	5	126.42	7.886e-3	4.917e-2
Phase 2 - plateau phase	Reactome	1	CACNA2D1	25	5	96.08	1.037e-2	5.824e-2
Phase 0 - rapid depolarisation	Reactome	1	CACNA2D1	44	5	54.59	1.819e-2	8.116e-2
Peroxisomal protein import	Reactome	1	MPV17	63	5	38.13	2.596e-2	9.965e-2
Peroxisome	KEGG	1	MPV17	83	5	28.94	3.409e-2	1.164e-1
Arrhythmogenic right ventricular cardiomyopathy	KEGG	1	CACNA2D1	86	5	27.93	3.530e-2	1.185e-1
Cardiac muscle contraction	KEGG	1	CACNA2D1	87	5	27.61	3.570e-2	1.193e-1
Hypertrophic cardiomyopathy	KEGG	1	CACNA2D1	99	5	24.26	4.055e-2	1.282e-1
Dilated cardiomyopathy	KEGG	1	CACNA2D1	105	5	22.88	4.296e-2	1.328e-1
Adrenergic signaling in cardiomyocytes	KEGG	1	CACNA2D1	154	5	15.60	6.250e-2	1.644e-1
Oxytocin signaling pathway	KEGG	1	CACNA2D1	154	5	15.60	6.250e-2	1.644e-1
Hormone signaling	KEGG	1	UCN	219	5	10.97	8.792e-2	2.004e-1
Cytoskeleton in muscle cells	KEGG	1	TRIM54	232	5	10.35	9.294e-2	2.071e-1