# GeDiPNet Cluster 6 -- Pairs Within Cluster -- generated 2026-10-09 19:53:46
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-09 03:00:13.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Ischemic heart disease	Myocardial ischemia	0.43367	170	1.828e-290	1.812e-287
Congestive heart failure	Heart failure	0.36268	173	1.014e-267	9.177e-265
Coronary artery disease	Myocardial infarction	0.23231	325	1.904e-223	9.912e-221
Coronary artery disease	Ischemic heart disease	0.14860	170	4.526e-198	1.597e-195
Coronary artery disease	Myocardial ischemia	0.18077	235	5.773e-168	1.321e-165
Cardiovascular disease	Hypertension	0.16153	220	5.382e-135	8.757e-133
Myocardial infarction	Myocardial ischemia	0.17391	144	1.097e-106	1.393e-104
Cardiovascular disease	Coronary artery disease	0.13709	190	1.368e-101	1.583e-99
Kidney disease	Kidney failure	0.17535	101	6.973e-93	6.571e-91
Cerebrovascular disorder	Stroke	0.17919	62	1.231e-87	1.072e-85
Coronary artery disease	Hypertension	0.14193	285	7.573e-83	6.258e-81
Atrial fibrillation	Heart failure	0.12669	150	2.290e-74	1.721e-72
Ischemic heart disease	Myocardial infarction	0.12594	84	2.965e-74	2.221e-72
Coronary artery disease	Stroke	0.10467	139	3.708e-72	2.700e-70
Hypertension	Myocardial infarction	0.11613	180	1.553e-66	1.071e-64
Coronary artery disease	Heart failure	0.11081	161	1.562e-66	1.073e-64
Heart disease	Myocardial ischemia	0.13742	65	3.634e-65	2.441e-63
Heart failure	Stroke	0.12306	87	2.621e-58	1.555e-56
Cardiovascular disease	Myocardial infarction	0.11319	103	2.870e-54	1.607e-52
Cardiovascular disease	Myocardial ischemia	0.11201	83	1.048e-49	5.486e-48
Atherosclerosis	Myocardial ischemia	0.10846	50	1.648e-48	8.348e-47
Cardiovascular disease	Heart failure	0.10798	88	5.250e-48	2.609e-46
Peripheral vascular disease	Vascular disease	0.30303	20	3.088e-43	1.380e-41
Congestive heart failure	Kidney failure	0.11948	46	1.790e-42	7.896e-41
Atrial fibrillation	Coronary artery disease	0.10093	184	1.259e-41	5.495e-40
Kidney failure	Myocardial ischemia	0.10103	59	2.170e-40	9.165e-39
Ischemic heart disease	Kidney failure	0.10761	41	1.276e-36	4.929e-35
Heart disease	Ischemic heart disease	0.12014	34	6.645e-36	2.486e-34
Atrial fibrillation	Hypertension	0.09402	173	4.260e-35	1.543e-33
Atherosclerosis	Ischemic heart disease	0.11111	29	2.730e-31	8.680e-30
Hypertension	Kidney disease	0.07362	108	5.452e-31	1.710e-29
Atherosclerosis	Congestive heart failure	0.09926	27	1.286e-27	3.579e-26
Coronary artery disease	Venous thromboembolism	0.06447	90	2.682e-27	7.349e-26
Atherosclerosis	Cerebrovascular disorder	0.11475	21	1.544e-26	4.143e-25
Coronary artery disease	Migraine	0.06538	95	8.954e-25	2.166e-23
Arteriosclerosis	Ischemic heart disease	0.08718	17	2.868e-23	6.367e-22
Endometriosis	Migraine	0.07133	52	3.129e-23	6.941e-22
Cerebrovascular disorder	Heart disease	0.09479	20	5.804e-23	1.254e-21
Cerebrovascular disorder	Vascular disease	0.12295	15	1.153e-22	2.455e-21
Heart disease	Large artery stroke	0.09223	19	4.560e-22	9.467e-21
Kidney disease	Myocardial infarction	0.06794	64	9.054e-22	1.865e-20
Hypertension	Migraine	0.06148	90	1.270e-21	2.602e-20
Arteriosclerosis	Atherosclerosis	0.09524	14	3.651e-20	7.026e-19
Ischemic heart disease	Large artery stroke	0.07328	17	8.365e-18	1.420e-16
Peripheral arterial disease	Peripheral vascular disease	0.06566	13	1.839e-17	3.079e-16
Migraine	Myocardial infarction	0.06028	56	1.855e-17	3.103e-16
Atherosclerosis	Vascular disease	0.08176	13	8.833e-17	1.425e-15
Migraine	Stroke	0.05814	40	2.391e-16	3.735e-15
Peripheral arterial disease	Vascular disease	0.06481	14	5.060e-16	7.686e-15
Cerebrovascular disorder	Peripheral vascular disease	0.09259	10	1.122e-15	1.675e-14
Heart disease	Vascular disease	0.06989	13	1.346e-15	1.999e-14
Cerebrovascular disorder	Peripheral arterial disease	0.06504	16	1.516e-15	2.243e-14
Cerebrovascular disorder	Large artery stroke	0.07947	12	9.983e-15	1.402e-13
Stroke	Venous thromboembolism	0.05380	34	4.349e-14	5.787e-13
Peripheral arterial disease	Stroke	0.05031	24	3.493e-13	4.398e-12
Large artery stroke	Peripheral vascular disease	0.07692	8	3.760e-12	4.277e-11
Endometriosis	Hypertension	0.04592	67	1.617e-11	1.753e-10
Cardiovascular disease	Preeclampsia	0.03711	19	2.478e-11	2.623e-10
Myocardial infarction	Venous thromboembolism	0.04649	41	5.124e-11	5.257e-10
Atherosclerosis	Peripheral arterial disease	0.04947	14	8.685e-11	8.721e-10
Hypertension	Venous thromboembolism	0.04190	60	3.599e-10	3.413e-9
Brain aneurysm	Migraine	0.03361	16	8.106e-10	7.388e-9
Kidney failure	Preeclampsia	0.03550	12	6.360e-8	4.618e-7
Ischemic heart disease	Preeclampsia	0.03861	10	1.252e-7	8.695e-7
Atherosclerosis	Erectile dysfunction	0.03429	6	7.368e-6	3.722e-5
Large artery stroke	Moyamoya disease	0.03676	5	1.513e-5	7.297e-5
Erectile dysfunction	Heart disease	0.02970	6	2.370e-5	1.115e-4
Brain aneurysm	Peripheral vascular disease	0.03419	4	3.433e-5	1.584e-4
Moyamoya disease	Peripheral vascular disease	0.03226	3	3.112e-4	7.705e-4
Arteriosclerosis	Corneal injury	0.02381	1	2.663e-3	3.595e-3
Acetyl-coa carboxylase deficiency	Erectile dysfunction	0.01613	1	3.962e-3	5.014e-3
Charcot-Marie-Tooth disease type 4B2	Moyamoya disease	0.01587	1	4.026e-3	5.085e-3
Preeclampsia	Zaki syndrome	0.01010	1	6.364e-3	7.626e-3
Brain aneurysm	Trimethylaminuria	0.01124	1	1.127e-2	1.266e-2
Congestive heart failure	Yoon-bellen neurodevelopmental syndrome	0.00556	1	1.162e-2	1.305e-2
Acetyl-coa carboxylase deficiency	Congestive heart failure	0.00556	1	1.162e-2	1.305e-2
Congestive heart failure	phosphoenolpyruvate carboxykinase deficiency, cytosolic	0.00556	1	1.162e-2	1.305e-2
Charcot-Marie-Tooth disease type 4B2	Congestive heart failure	0.00556	1	1.162e-2	1.305e-2
Intellectual developmental disorder growth metabolic	Venous thromboembolism	0.00292	1	2.221e-2	2.404e-2
Migraine	Trichilemmal cyst	0.00247	1	2.624e-2	2.801e-2
Kidney disease	Peho-like syndrome	0.00235	1	2.760e-2	2.941e-2
Heart failure	phosphoenolpyruvate carboxykinase deficiency, cytosolic	0.00212	1	3.052e-2	3.240e-2
Heart failure	Yoon-bellen neurodevelopmental syndrome	0.00212	1	3.052e-2	3.240e-2
Acetyl-coa carboxylase deficiency	Heart failure	0.00212	1	3.052e-2	3.240e-2
Atrial fibrillation	Hemorrhagic destruction of the brain subependymal calcification and cataracts	0.00116	1	5.605e-2	5.765e-2
Atrial fibrillation	band heterotopia of brain	0.00116	1	5.605e-2	5.765e-2
Coronary artery disease	Intellectual developmental disorder growth metabolic	0.00087	1	7.423e-2	7.553e-2
band heterotopia of brain	Coronary artery disease	0.00087	1	7.423e-2	7.553e-2
Hypertension	Trimethylaminuria	0.00087	1	1.437e-1	1.449e-1