# GeDiPNet Cluster 584 -- Enriched Pathways -- generated 2026-10-19 23:22:15
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-20 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Endocrine resistance	KEGG	4	TP53, CDKN2A, KRAS, GNAS	99	11	44.11	1.371e-6	5.491e-5
Bladder cancer	KEGG	3	TP53, CDKN2A, KRAS	41	11	79.89	5.979e-6	1.906e-4
Cellular senescence	KEGG	4	TP53, CDKN2A, RRAS2, KRAS	157	11	27.82	8.636e-6	2.585e-4
Hepatocellular carcinoma	KEGG	4	TP53, ARID1A, CDKN2A, KRAS	170	11	25.69	1.183e-5	3.346e-4
Proteoglycans in cancer	KEGG	4	TP53, ANK1, RRAS2, KRAS	204	11	21.41	2.429e-5	6.122e-4
Melanoma	KEGG	3	TP53, CDKN2A, KRAS	73	11	44.87	3.433e-5	8.103e-4
Non-small cell lung cancer	KEGG	3	TP53, CDKN2A, KRAS	73	11	44.87	3.433e-5	8.103e-4
Human cytomegalovirus infection	KEGG	4	TP53, CDKN2A, KRAS, GNAS	226	11	19.32	3.632e-5	8.462e-4
Glioma	KEGG	3	TP53, CDKN2A, KRAS	76	11	43.10	3.874e-5	8.916e-4
Pancreatic cancer	KEGG	3	TP53, CDKN2A, KRAS	77	11	42.54	4.029e-5	9.199e-4
Chronic myeloid leukemia	KEGG	3	TP53, CDKN2A, KRAS	77	11	42.54	4.029e-5	9.199e-4
Stabilization of p53	Reactome	2	TP53, CDKN2A	11	11	198.51	4.176e-5	9.469e-4
Longevity regulating pathway	KEGG	3	TP53, IRS4, KRAS	90	11	36.39	6.429e-5	1.333e-3
Mitophagy - animal	KEGG	3	TP53, RRAS2, KRAS	105	11	31.19	1.018e-4	1.923e-3
SUMOylation of transcription factors	Reactome	2	TP53, CDKN2A	18	11	121.31	1.158e-4	2.128e-3