# GeDiPNet Cluster 57 -- Top Shared Genes -- generated 2026-10-07 04:10:31
# Curated genes (disease_gdp) linked to 2 or more of this cluster's member diseases, most widely shared first. Data as of: 2026-10-07 03:15:01.
Gene	Member Diseases Linked	Cluster Size	Linked Diseases
LDLR	7	15	Arteriosclerosis; Dyslipidemias; Hypercholesterolemia; hypercholesterolemia, familial, 1; Hyperlipidemia; Hyperlipoproteinemia; Lipoprotein lipase deficiency
APOB	6	15	Arteriosclerosis; Hypercholesterolemia; Hyperlipidemia; Hyperlipoproteinemia; Hypertriglyceridemia; Lipoprotein lipase deficiency
LPL	6	15	Dyslipidemias; Hypercholesterolemia; Hyperlipidemia; Hyperlipoproteinemia; Hypertriglyceridemia; Lipoprotein lipase deficiency
APOA5	5	15	Apolipoprotein a5 deficiency; Hyperlipidemia; Hyperlipoproteinemia; Hypertriglyceridemia; Lipoprotein lipase deficiency
APOE	5	15	Arteriosclerosis; Hypercholesterolemia; Hyperlipidemia; Hyperlipoproteinemia; Lipoprotein lipase deficiency
CETP	4	15	Hyperlipidemia; Hyperlipoproteinemia; Hypertriglyceridemia; Lipoprotein lipase deficiency
PCSK9	4	15	Hypercholesterolemia; Hyperlipidemia; Hyperlipoproteinemia; Lipoprotein lipase deficiency
PPARA	4	15	Dyslipidemias; Hyperlipidemia; Hyperlipoproteinemia; Hypertriglyceridemia
ZPR1	4	15	Growth restriction, hypoplastic kidneys, alopecia, and distinctive facies; Hyperlipidemia; Hypertriglyceridemia; Lipoprotein lipase deficiency
ABCA1	3	15	Hypercholesterolemia; Hyperlipidemia; Hyperlipoproteinemia
ABCG8	3	15	Arteriosclerosis; Hyperlipidemia; Hyperlipoproteinemia
ADRB2	3	15	Hypercholesterolemia; Hyperlipidemia; Hyperlipoproteinemia
APOC3	3	15	Hypercholesterolemia; Hyperlipidemia; Hyperlipoproteinemia
GALNT2	3	15	congenital disorder of glycosylation, type iit; Hyperlipidemia; Lipoprotein lipase deficiency
GCKR	3	15	Hyperlipidemia; Hypertriglyceridemia; Lipoprotein lipase deficiency
HMGCR	3	15	Hypercholesterolemia; Hyperlipidemia; Hyperlipoproteinemia
LDLRAP1	3	15	Hypercholesterolemia; hypercholesterolemia, familial, 4; Hyperlipoproteinemia
LEPR	3	15	Dyslipidemias; Hyperlipidemia; Hyperlipoproteinemia
LIPC	3	15	Hypercholesterolemia; Hyperlipidemia; Hyperlipoproteinemia
NEIL1	3	15	Dyslipidemias; Hyperlipidemia; Hyperlipoproteinemia
NOS3	3	15	Arteriosclerosis; Hyperlipidemia; Hyperlipoproteinemia
PLTP	3	15	Dyslipidemias; Hyperlipidemia; Hypertriglyceridemia
PON1	3	15	Arteriosclerosis; Hypercholesterolemia; Hyperlipoproteinemia
TDRD15	3	15	Hyperlipidemia; Hypertriglyceridemia; Lipoprotein lipase deficiency
ABCB1	2	15	Hyperlipidemia; Hyperlipoproteinemia
ABCG5	2	15	Arteriosclerosis; Hypercholesterolemia
ADRB3	2	15	Hyperlipidemia; Hyperlipoproteinemia
ALDH3A1	2	15	Arteriosclerosis; Corneal injury
ANGPTL4	2	15	Hyperlipidemia; Hypertriglyceridemia
APC	2	15	Hyperlipidemia; Hyperlipoproteinemia
APOA2	2	15	Hypercholesterolemia; Hyperlipoproteinemia
APOA4	2	15	Hypercholesterolemia; Hyperlipoproteinemia
APOC1	2	15	Hyperlipidemia; Lipoprotein lipase deficiency
APOC2	2	15	Hyperlipidemia; Hyperlipoproteinemia
CCL2	2	15	Hyperlipidemia; Hyperlipoproteinemia
CELSR2	2	15	Hyperlipidemia; Lipoprotein lipase deficiency
CREB3L3	2	15	Hypertriglyceridemia; Infantile hypertriglyceridemia with hepatosteatosis
CYP7A1	2	15	Hypercholesterolemia; Hyperlipidemia
DOCK7	2	15	Hyperlipidemia; Lipoprotein lipase deficiency
EPHX2	2	15	Hypercholesterolemia; Hyperlipoproteinemia
FADS1	2	15	Hyperlipidemia; Lipoprotein lipase deficiency
FADS2	2	15	Hyperlipidemia; Lipoprotein lipase deficiency
GCG	2	15	Hyperlipidemia; Hyperlipoproteinemia
GHR	2	15	Hypercholesterolemia; Hyperlipoproteinemia
GNB3	2	15	Hyperlipidemia; Hyperlipoproteinemia
GPD1	2	15	Hypertriglyceridemia; Infantile hypertriglyceridemia with hepatosteatosis
HAVCR1	2	15	Hyperlipidemia; Hypertriglyceridemia
HSPA1B	2	15	Hyperlipidemia; Hyperlipoproteinemia
ICAM1	2	15	Arteriosclerosis; Hypercholesterolemia
IRS1	2	15	Hyperlipidemia; Hyperlipoproteinemia
LMX1B	2	15	Hyperlipidemia; Hyperlipoproteinemia
LPA	2	15	Hypercholesterolemia; Hyperlipidemia
MLXIPL	2	15	Hyperlipidemia; Lipoprotein lipase deficiency
NAT2	2	15	Hyperlipidemia; Lipoprotein lipase deficiency
NR5A2	2	15	Anovulation; Dyslipidemias
NYAP2	2	15	Hyperlipidemia; Lipoprotein lipase deficiency
PDE1C	2	15	Hypercholesterolemia; Hyperlipoproteinemia
PON2	2	15	Hypercholesterolemia; Hyperlipoproteinemia
PPARGC1B	2	15	Hyperlipidemia; Hyperlipoproteinemia
PPP1R17	2	15	Hypercholesterolemia; Hyperlipoproteinemia
PSD3	2	15	Hyperlipidemia; Lipoprotein lipase deficiency
SMARCA4	2	15	Hyperlipidemia; Lipoprotein lipase deficiency
TOMM40	2	15	Dyslipidemias; Hyperlipidemia
VCAM1	2	15	Arteriosclerosis; Hypercholesterolemia
VEGFA	2	15	Hyperlipidemia; Lipoprotein lipase deficiency