# GeDiPNet Cluster 553 -- Enriched Pathways -- generated 2026-10-19 23:22:17
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-20 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Molybdenum cofactor biosynthesis	Reactome	2	MOCS1, MOCS2	6	4	1000.83	1.247e-6	5.046e-5
Folate biosynthesis	KEGG	2	MOCS1, MOCS2	28	4	214.46	3.136e-5	7.518e-4
Virion - Rotavirus	KEGG	1	ITGA2	2	4	1501.25	6.660e-4	8.310e-3
Biosynthesis of cofactors	KEGG	2	MOCS1, MOCS2	154	4	38.99	9.637e-4	1.102e-2
Cytoskeleton in muscle cells	KEGG	2	DAAM2, ITGA2	232	4	25.88	2.173e-3	2.024e-2
Sulfur relay system	KEGG	1	MOCS2	8	4	375.31	2.662e-3	2.343e-2
Syndecan interactions	Reactome	1	ITGA2	16	4	187.66	5.319e-3	3.801e-2
Laminin interactions	Reactome	1	ITGA2	28	4	107.23	9.294e-3	5.428e-2
MET activates PTK2 signaling	Reactome	1	ITGA2	30	4	100.08	9.956e-3	5.666e-2
ECM proteoglycans	Reactome	1	ITGA2	51	4	58.87	1.688e-2	7.780e-2
Integrin cell surface interactions	Reactome	1	ITGA2	81	4	37.07	2.671e-2	1.011e-1
Arrhythmogenic right ventricular cardiomyopathy	KEGG	1	ITGA2	86	4	34.91	2.834e-2	1.046e-1
ECM-receptor interaction	KEGG	1	ITGA2	89	4	33.74	2.932e-2	1.069e-1
Small cell lung cancer	KEGG	1	ITGA2	93	4	32.28	3.062e-2	1.097e-1
Hypertrophic cardiomyopathy	KEGG	1	ITGA2	99	4	30.33	3.257e-2	1.134e-1