# GeDiPNet Cluster 52 -- Pairs Within Cluster -- generated 2026-10-07 17:38:08
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 17:17:47.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Microphthalmia	Microphthalmos	0.38889	21	9.450e-49	4.821e-47
Colobomatous microphthalmia	Microphthalmia	0.38462	15	3.141e-41	1.360e-39
Colobomatous microphthalmia	Microphthalmos	0.33333	13	5.536e-34	1.946e-32
Anophthalmia/microphthalmia-esophageal atresia syndrome	Microphthalmia	0.20755	11	1.821e-23	4.109e-22
Anophthalmia	Microphthalmos	0.21429	9	1.398e-21	2.864e-20
Anophthalmia	Microphthalmia	0.20455	9	2.419e-21	4.893e-20
Anophthalmia/microphthalmia-esophageal atresia syndrome	Microphthalmos	0.19231	10	3.944e-21	7.940e-20
Anophthalmia	Anophthalmia/microphthalmia-esophageal atresia syndrome	0.25000	8	4.127e-20	7.949e-19
Microphthalmia	Nanophthalmos	0.18605	8	3.073e-19	5.614e-18
Anophthalmia/microphthalmia-esophageal atresia syndrome	Colobomatous microphthalmia	0.20588	7	7.545e-17	1.225e-15
Congenital cystic eyeball	Microphthalmos	0.16216	6	1.053e-16	1.697e-15
Congenital cystic eyeball	Microphthalmia	0.15385	6	1.493e-16	2.380e-15
Anophthalmia	Colobomatous microphthalmia	0.25000	6	8.094e-16	1.223e-14
Colobomatous microphthalmia	Congenital cystic eyeball	0.29412	5	2.498e-15	3.644e-14
Microphthalmos	Nanophthalmos	0.13953	6	9.634e-14	1.249e-12
Colobomatous microphthalmia	Nanophthalmos	0.21739	5	3.287e-13	4.169e-12
Congenital cystic eyeball	Nanophthalmos	0.18750	3	7.223e-9	6.039e-8
Microphthalmia with retinitis pigmentosa and ocular anomalies	Nanophthalmos	0.15385	2	5.568e-7	3.416e-6
Anophthalmia/microphthalmia-esophageal atresia syndrome	Colobomatous optic disc macular atrophy chorioretinopathy syndrome	0.07692	2	2.531e-6	1.387e-5
Congenital cystic eyeball	Klippel-feil syndrome	0.16667	2	2.655e-6	1.449e-5
Colobomatous optic disc macular atrophy chorioretinopathy syndrome	Microphthalmia	0.05128	2	5.930e-6	3.045e-5
Microphthalmia	Microphthalmia with retinitis pigmentosa and ocular anomalies	0.05128	2	5.930e-6	3.045e-5
Colobomatous microphthalmia	Klippel-feil syndrome	0.09524	2	1.855e-5	8.859e-5
Congenital cystic eyeball	isolated microphthalmia 6	0.14286	1	3.897e-4	8.637e-4
Nanophthalmos	nanophthalmos 4	0.07692	1	7.793e-4	1.404e-3
isolated microphthalmia 6	Nanophthalmos	0.07692	1	7.793e-4	1.404e-3
Colobomatous microphthalmia	colobomatous microphthalmia-rhizomelic dysplasia syndrome	0.06250	1	9.742e-4	1.663e-3
Colobomatous microphthalmia	Focal dermal hypoplasia	0.06250	1	9.742e-4	1.663e-3
Colobomatous optic disc macular atrophy chorioretinopathy syndrome	Nanophthalmos	0.07143	1	1.558e-3	2.374e-3
Anophthalmia/microphthalmia-esophageal atresia syndrome	Focal dermal hypoplasia	0.03846	1	1.624e-3	2.459e-3
Colobomatous microphthalmia	Colobomatous optic disc macular atrophy chorioretinopathy syndrome	0.05882	1	1.947e-3	2.826e-3
isolated microphthalmia 6	Microphthalmos	0.02703	1	2.338e-3	3.242e-3
Focal dermal hypoplasia	Microphthalmos	0.02703	1	2.338e-3	3.242e-3
isolated microphthalmia 6	Microphthalmia	0.02564	1	2.468e-3	3.370e-3
Focal dermal hypoplasia	Microphthalmia	0.02564	1	2.468e-3	3.370e-3
colobomatous microphthalmia-rhizomelic dysplasia syndrome	Microphthalmia	0.02564	1	2.468e-3	3.370e-3
Microphthalmia	X-linked colobomatous microphthalmia, microcephaly, intellectual disability, short stature syndrome	0.02564	1	2.468e-3	3.370e-3
Microphthalmia with retinitis pigmentosa and ocular anomalies	Microphthalmos	0.02632	1	4.671e-3	5.786e-3