# GeDiPNet Cluster 499 -- Pairs Within Cluster -- generated 2026-10-19 23:21:09
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-20 03:00:19.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
East syndrome	Seizures, sensorineural deafness, ataxia, impaired intellectual development, and electrolyte imbalance	0.50000	1	6.457e-5	1.985e-4
East syndrome	Sesame syndrome	0.50000	1	6.457e-5	1.985e-4
Seizures, sensorineural deafness, ataxia, impaired intellectual development, and electrolyte imbalance	Sesame syndrome	0.50000	1	6.457e-5	1.985e-4
East syndrome	Seizures, tonic-clonic, photosensitive	0.33333	1	1.291e-4	3.269e-4
Seizures, sensorineural deafness, ataxia, impaired intellectual development, and electrolyte imbalance	Seizures, tonic-clonic, photosensitive	0.33333	1	1.291e-4	3.269e-4
Seizures, tonic-clonic, photosensitive	Sesame syndrome	0.33333	1	1.291e-4	3.269e-4
East syndrome	Enlarged vestibular aqueduct	0.25000	1	1.937e-4	4.414e-4
Enlarged vestibular aqueduct	Seizures, sensorineural deafness, ataxia, impaired intellectual development, and electrolyte imbalance	0.25000	1	1.937e-4	4.414e-4
Enlarged vestibular aqueduct	Sesame syndrome	0.25000	1	1.937e-4	4.414e-4
East syndrome	Littles disease	0.16667	1	3.228e-4	6.412e-4
Littles disease	Seizures, sensorineural deafness, ataxia, impaired intellectual development, and electrolyte imbalance	0.16667	1	3.228e-4	6.412e-4
Littles disease	Sesame syndrome	0.16667	1	3.228e-4	6.412e-4
Enlarged vestibular aqueduct	Seizures, tonic-clonic, photosensitive	0.20000	1	3.874e-4	7.329e-4