# GeDiPNet Cluster 496 -- Pairs Within Cluster -- generated 2026-10-19 23:21:10
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-20 03:00:19.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome	Overgrowth syndrome and/or cerebral malformations due to abnormalities in MTOR pathway genes	0.40000	2	7.504e-8	5.341e-7
Hemimegalencephaly	Overgrowth syndrome and/or cerebral malformations due to abnormalities in MTOR pathway genes	0.25000	2	3.752e-7	2.417e-6
Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	0.25000	1	1.937e-4	4.414e-4
Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3	0.25000	1	1.937e-4	4.414e-4
Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	0.25000	1	1.937e-4	4.414e-4
Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Overgrowth syndrome and/or cerebral malformations due to abnormalities in MTOR pathway genes	0.25000	1	1.937e-4	4.414e-4
Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Overgrowth syndrome and/or cerebral malformations due to abnormalities in MTOR pathway genes	0.25000	1	1.937e-4	4.414e-4
Hemimegalencephaly	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	0.14286	1	3.874e-4	7.329e-4
Hemimegalencephaly	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome	0.11111	1	1.162e-3	1.729e-3