# GeDiPNet Cluster 490 -- Pairs Within Cluster -- generated 2026-10-19 23:20:23
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-20 03:00:19.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Colorectal cancer susceptibility	Polyposis and colorectal cancer syndrome	0.40000	2	5.003e-8	3.625e-7
Mandibular hypoplasia-deafness-progeroid syndrome	Subcutaneous lipodystrophy, deafness, mandibular hypoplasia and male hypogonadism	0.50000	1	6.457e-5	1.985e-4
Mandibular hypoplasia-deafness-progeroid syndrome	Polyposis and colorectal cancer syndrome	0.33333	1	1.291e-4	3.269e-4
Mandibular hypoplasia-deafness-progeroid syndrome	Non-severe combined immunodeficiency due to polymerase delta deficiency	0.33333	1	1.291e-4	3.269e-4
Non-severe combined immunodeficiency due to polymerase delta deficiency	Subcutaneous lipodystrophy, deafness, mandibular hypoplasia and male hypogonadism	0.33333	1	1.291e-4	3.269e-4
Polyposis and colorectal cancer syndrome	Subcutaneous lipodystrophy, deafness, mandibular hypoplasia and male hypogonadism	0.33333	1	1.291e-4	3.269e-4
Non-severe combined immunodeficiency due to polymerase delta deficiency	Polyposis and colorectal cancer syndrome	0.25000	1	2.583e-4	5.384e-4
Colorectal cancer susceptibility	Mandibular hypoplasia-deafness-progeroid syndrome	0.20000	1	2.583e-4	5.384e-4
Colorectal cancer susceptibility	Subcutaneous lipodystrophy, deafness, mandibular hypoplasia and male hypogonadism	0.20000	1	2.583e-4	5.384e-4
Colorectal cancer susceptibility	Non-severe combined immunodeficiency due to polymerase delta deficiency	0.16667	1	5.165e-4	9.125e-4
Colorectal cancer susceptibility	Paraquat lung disease	0.14286	1	7.746e-4	1.247e-3