# GeDiPNet Cluster 490 -- Top Shared Genes -- generated 2026-10-20 00:01:29
# Curated genes (disease_gdp) linked to 2 or more of this cluster's member diseases, most widely shared first. Data as of: 2026-10-20 03:15:01.
Gene	Member Diseases Linked	Cluster Size	Linked Diseases
POLD1	5	6	Colorectal cancer susceptibility; Mandibular hypoplasia-deafness-progeroid syndrome; Non-severe combined immunodeficiency due to polymerase delta deficiency; Polyposis and colorectal cancer syndrome; Subcutaneous lipodystrophy, deafness, mandibular hypoplasia and male hypogonadism
POLE	2	6	Colorectal cancer susceptibility; Polyposis and colorectal cancer syndrome
SMAD7	2	6	Colorectal cancer susceptibility; Paraquat lung disease