# GeDiPNet Cluster 48 -- Pairs Within Cluster -- generated 2026-10-07 10:33:50
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:00:12.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Focal cortical dysplasia	Tuberous sclerosis complex	0.40000	4	2.242e-13	3.021e-12
Polycystic kidney disease with tuberous sclerosis	Polycystic kidneys, severe infantile with tuberous sclerosis	0.66667	2	8.436e-9	7.203e-8
Polycystic kidneys, severe infantile with tuberous sclerosis	Tuberous sclerosis complex	0.28571	2	1.265e-7	9.200e-7
Polycystic kidney disease with tuberous sclerosis	Tuberous sclerosis complex	0.28571	2	1.265e-7	9.200e-7
Focal cortical dysplasia	Polycystic kidneys, severe infantile with tuberous sclerosis	0.25000	2	1.772e-7	1.249e-6
Focal cortical dysplasia	Polycystic kidney disease with tuberous sclerosis	0.25000	2	1.772e-7	1.249e-6
Adenomatous polyposis	Tuberous sclerosis complex	0.18182	2	1.897e-6	1.122e-5
Adenomatous polyposis	Focal cortical dysplasia	0.16667	2	2.655e-6	1.527e-5
Liver cyst	Polycystic kidney disease with tuberous sclerosis	0.33333	1	1.299e-4	3.898e-4
Liver cyst	Polycystic kidneys, severe infantile with tuberous sclerosis	0.33333	1	1.299e-4	3.898e-4
Liver cyst	Renovascular hypertension	0.33333	1	1.299e-4	3.898e-4
Congenital kidney anomaly	Liver cyst	0.25000	1	1.948e-4	5.278e-4
CEP290-related ciliopathy	Congenital kidney anomaly	0.25000	1	1.948e-4	5.278e-4
Polycystic kidney disease with tuberous sclerosis	Renovascular hypertension	0.25000	1	2.598e-4	6.403e-4
Polycystic kidneys, severe infantile with tuberous sclerosis	Renovascular hypertension	0.25000	1	2.598e-4	6.403e-4
Encephalocele	joubert syndrome 17	0.20000	1	2.598e-4	6.403e-4
Xanthinuria	xanthinuria type II	0.20000	1	2.598e-4	6.403e-4
CEP290-related ciliopathy	Encephalocele	0.20000	1	2.598e-4	6.403e-4
Congenital kidney anomaly	Renovascular hypertension	0.20000	1	3.896e-4	8.521e-4
Congenital kidney anomaly	Polycystic kidney disease with tuberous sclerosis	0.20000	1	3.896e-4	8.521e-4
Adenomatous polyposis	familial adenomatous polyposis 4	0.14286	1	3.897e-4	8.521e-4
Adenomatous polyposis	Folic acid deficiency	0.14286	1	3.897e-4	8.521e-4
Adenomatous polyposis	NTHL1-deficiency tumor predisposition syndrome	0.14286	1	3.897e-4	8.521e-4
NTHL1-deficiency tumor predisposition syndrome	Tuberous sclerosis complex	0.14286	1	3.897e-4	8.521e-4
Focal cortical dysplasia	NTHL1-deficiency tumor predisposition syndrome	0.12500	1	4.546e-4	9.545e-4
Polycystic kidney disease with tuberous sclerosis	Xanthinuria	0.16667	1	5.195e-4	1.041e-3
Polycystic kidneys, severe infantile with tuberous sclerosis	Xanthinuria	0.16667	1	5.195e-4	1.041e-3
Congenital kidney anomaly	Encephalocele	0.14286	1	7.792e-4	1.386e-3
Adenomatous polyposis	Xanthinuria	0.10000	1	1.558e-3	2.360e-3