# GeDiPNet Cluster 470 -- Enriched Pathways -- generated 2026-10-19 23:22:15
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-20 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Cytokine-cytokine receptor interaction	KEGG	3	IL17RC, IL23R, IL12RB2	298	4	30.23	5.939e-5	1.251e-3
Inflammatory bowel disease	KEGG	2	IL23R, IL12RB2	66	4	90.98	1.772e-4	2.984e-3
JAK-STAT signaling pathway	KEGG	2	IL23R, IL12RB2	168	4	35.74	1.146e-3	1.257e-2
Interleukin-17 signaling	Reactome	1	IL17RC	8	4	375.31	2.662e-3	2.343e-2
Interleukin-23 signaling	Reactome	1	IL23R	9	4	333.61	2.995e-3	2.538e-2
Interleukin-12 signaling	Reactome	1	IL12RB2	10	4	300.25	3.327e-3	2.738e-2
Interleukin-35 Signalling	Reactome	1	IL12RB2	12	4	250.21	3.991e-3	3.122e-2
Pathways in cancer	KEGG	2	IL23R, IL12RB2	533	4	11.27	1.111e-2	6.071e-2
CLEC7A (Dectin-1) signaling	Reactome	1	CARD9	79	4	38.01	2.606e-2	9.987e-2
Th1 and Th2 cell differentiation	KEGG	1	IL12RB2	93	4	32.28	3.062e-2	1.097e-1
IL-17 signaling pathway	KEGG	1	IL17RC	94	4	31.94	3.095e-2	1.102e-1
C-type lectin receptor signaling pathway	KEGG	1	CARD9	105	4	28.60	3.452e-2	1.169e-1
Interleukin-4 and Interleukin-13 signaling	Reactome	1	IL23R	108	4	27.80	3.549e-2	1.188e-1
Th17 cell differentiation	KEGG	1	IL23R	109	4	27.55	3.582e-2	1.195e-1
Alcoholic liver disease	KEGG	1	IL17RC	144	4	20.85	4.711e-2	1.399e-1