# GeDiPNet Cluster 47 -- Enriched GO Terms (Biological Process) -- generated 2026-10-07 15:04:24
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:23:06.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
immune response	GO:0006955	155	ACKR3, BMP6, CCL21, CCL8, CCR6, CD2, CD244, CD28, CIITA, CSF2, CTLA4, CXCL2	543	1725	3.09	2.716e-39	2.794e-35
inflammatory response	GO:0006954	131	ADORA2A, AGER, ALOX5, BDKRB2, BMP6, CCL21, CCL8, CD40, CRP, CXCL2, CXCL6, CXCL8	467	1725	3.04	2.028e-32	1.267e-28
positive regulation of type II interferon production	GO:0032729	39	CD2, CD244, CD3E, HLA-DPB1, IL18, IL1B, IL23A, IRF8, PTPN22, SLC11A1, TNF, TYK2	77	1725	5.49	1.217e-20	2.183e-17
immune system process	GO:0002376	175	CD244, CD28, CD3E, CD40, CD83, CTLA4, FCGR2A, GATA3, HLA-DPB1, HLA-DQA2, HLA-DRB1, IL23A	943	1725	2.01	5.255e-20	8.589e-17
positive regulation of transcription by RNA polymerase II	GO:0045944	207	AHR, BMP4, BMP6, CCN1, CD28, CD40, CIITA, FOXP3, GATA3, HCLS1, HDAC1, HOXD10	1208	1725	1.86	2.487e-19	3.640e-16
positive regulation of T cell proliferation	GO:0042102	34	CD28, CD3E, HLA-DPB1, IL1B, IL23A, IL2RA, IL6, IL6ST, PTPRC, TRAF6, TYK2, CCDC88B	67	1725	5.50	3.326e-18	4.104e-15
positive regulation of MAPK cascade	GO:0043410	65	CAV2, CD3E, CD40, GSDME, HLA-DRB1, IGFBP3, IL1B, IL6, IL6R, PTPRC, TNF, VEGFA	224	1725	3.14	1.830e-17	2.046e-14
positive regulation of tumor necrosis factor production	GO:0032760	43	AGER, CD2, CYBB, FCGR2A, IFNG, IL23A, IL6, LY96, MIF, PTPRC, TLR2, CARD9	113	1725	4.12	9.570e-17	9.298e-14
cell surface receptor signaling pathway via JAK-STAT	GO:0007259	32	CD40, CSF2, IFNG, IL23A, IL6, IL6R, IL6ST, STAT1, STAT4, TNF, TYK2, IL23R	67	1725	5.17	3.179e-16	2.752e-13
positive regulation of T cell activation	GO:0050870	26	CD28, CD3E, HLA-DPB1, HLA-DQA2, HLA-DRB1, PRKCQ, CCDC88B, HLA-DMB, HLA-DOA, HLA-DPA1, HLA-DQB1, B2M	45	1725	6.26	4.491e-16	3.768e-13
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	GO:0051897	61	CAT, CCL21, CD28, F2, GATA3, HCLS1, IL18, IL1B, PTK2, TNF, VEGFA, ERBB3	217	1725	3.05	9.340e-16	7.293e-13
cytokine-mediated signaling pathway	GO:0019221	48	IL18, IL1B, IL2RB, IL6, IL6R, IL6ST, IRAK1, IRF5, STAT4, TYK2, FLT3, IL23R	145	1725	3.59	1.028e-15	7.906e-13
positive regulation of smooth muscle cell proliferation	GO:0048661	27	BMP4, HDAC1, IL18, IL6, IL6R, IRAK1, MMP2, NR4A3, STAT1, TNF, CCN4, ITGB3	52	1725	5.62	4.613e-15	3.201e-12
positive regulation of cell population proliferation	GO:0008284	107	AGER, BMP4, BMP6, CSF2, F2, FASLG, HCLS1, HDAC1, IFNG, IL1B, IL6, IL6R	532	1725	2.18	5.678e-15	3.864e-12
positive regulation of canonical NF-kappaB signal transduction	GO:0043123	62	ADIPOQ, CCL21, CD40, FASLG, HLA-DRB1, IL1B, IRAK1, REL, TLR2, TNF, TNFSF14, TRAF6	232	1725	2.90	7.300e-15	4.818e-12