# GeDiPNet Cluster 465 -- Pairs Within Cluster -- generated 2026-10-20 00:02:18
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected across all tested pairs. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-20 03:00:19.
Disease A	Disease B	Similarity Score	Shared Genes	P-value	FDR Q-value
Keratosis follicularis spinulosa decalvans, x-linked	Olmsted syndrome, x-linked	0.66667	2	8.338e-9	6.596e-8
Brain anomalies ectodermal dysplasia skeletal malformations hirschsprung disease syndrome	Bresek syndrome	0.50000	1	6.457e-5	1.985e-4
Brain anomalies ectodermal dysplasia skeletal malformations hirschsprung disease syndrome	Ifap syndrome 1, with or without bresheck syndrome	0.50000	1	6.457e-5	1.985e-4
Brain anomalies ectodermal dysplasia skeletal malformations hirschsprung disease syndrome	Ichthyosis follicularis, atrichia, and photophobia with or without brain anomalies, retardation, ectodermal dysplasia, skeletal malformations, hirschsprung disease, ear/eye anomalies, cleft palate/cryptorchidism, and kidney dysplasia/hypoplasia	0.50000	1	6.457e-5	1.985e-4
Bresek syndrome	Ifap syndrome 1, with or without bresheck syndrome	0.50000	1	6.457e-5	1.985e-4
Bresek syndrome	Ichthyosis follicularis, atrichia, and photophobia with or without brain anomalies, retardation, ectodermal dysplasia, skeletal malformations, hirschsprung disease, ear/eye anomalies, cleft palate/cryptorchidism, and kidney dysplasia/hypoplasia	0.50000	1	6.457e-5	1.985e-4
Ichthyosis follicularis, atrichia, and photophobia with or without brain anomalies, retardation, ectodermal dysplasia, skeletal malformations, hirschsprung disease, ear/eye anomalies, cleft palate/cryptorchidism, and kidney dysplasia/hypoplasia	Ifap syndrome 1, with or without bresheck syndrome	0.50000	1	6.457e-5	1.985e-4
Brain anomalies ectodermal dysplasia skeletal malformations hirschsprung disease syndrome	Keratosis follicularis spinulosa decalvans, x-linked	0.33333	1	1.291e-4	3.269e-4
Brain anomalies ectodermal dysplasia skeletal malformations hirschsprung disease syndrome	Olmsted syndrome, x-linked	0.33333	1	1.291e-4	3.269e-4
Bresek syndrome	Keratosis follicularis spinulosa decalvans, x-linked	0.33333	1	1.291e-4	3.269e-4
Bresek syndrome	Olmsted syndrome, x-linked	0.33333	1	1.291e-4	3.269e-4
Ichthyosis follicularis, atrichia, and photophobia with or without brain anomalies, retardation, ectodermal dysplasia, skeletal malformations, hirschsprung disease, ear/eye anomalies, cleft palate/cryptorchidism, and kidney dysplasia/hypoplasia	Keratosis follicularis spinulosa decalvans, x-linked	0.33333	1	1.291e-4	3.269e-4
Ichthyosis follicularis, atrichia, and photophobia with or without brain anomalies, retardation, ectodermal dysplasia, skeletal malformations, hirschsprung disease, ear/eye anomalies, cleft palate/cryptorchidism, and kidney dysplasia/hypoplasia	Olmsted syndrome, x-linked	0.33333	1	1.291e-4	3.269e-4
Ifap syndrome 1, with or without bresheck syndrome	Keratosis follicularis spinulosa decalvans, x-linked	0.33333	1	1.291e-4	3.269e-4
Ifap syndrome 1, with or without bresheck syndrome	Olmsted syndrome, x-linked	0.33333	1	1.291e-4	3.269e-4