# GeDiPNet Cluster 450 -- Enriched Pathways -- generated 2026-10-19 23:22:12
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-20 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Non-small cell lung cancer	KEGG	4	MET, TP53, PIK3CA, JAK3	73	6	109.68	1.867e-8	1.284e-6
Gastric cancer	KEGG	4	MET, TP53, PIK3CA, TGFBR2	150	6	53.38	3.440e-7	1.648e-5
Hepatitis B	KEGG	4	TP53, PIK3CA, TGFBR2, JAK3	163	6	49.12	4.803e-7	2.207e-5
Hepatocellular carcinoma	KEGG	4	MET, TP53, PIK3CA, TGFBR2	170	6	47.10	5.686e-7	2.547e-5
Pathways in cancer	KEGG	5	MET, TP53, PIK3CA, TGFBR2, JAK3	533	6	18.78	9.773e-7	4.085e-5
Human T-cell leukemia virus 1 infection	KEGG	4	TP53, PIK3CA, TGFBR2, JAK3	224	6	35.74	1.716e-6	6.661e-5
MET activates PI3K/AKT signaling	Reactome	2	MET, PIK3CA	6	6	667.22	3.117e-6	1.102e-4
Central carbon metabolism in cancer	KEGG	3	MET, TP53, PIK3CA	71	6	84.58	3.910e-6	1.338e-4
Melanoma	KEGG	3	MET, TP53, PIK3CA	73	6	82.26	4.253e-6	1.436e-4
Pancreatic cancer	KEGG	3	TP53, PIK3CA, TGFBR2	77	6	77.99	4.999e-6	1.641e-4
Chronic myeloid leukemia	KEGG	3	TP53, PIK3CA, TGFBR2	77	6	77.99	4.999e-6	1.641e-4
Colorectal cancer	KEGG	3	TP53, PIK3CA, TGFBR2	87	6	69.02	7.229e-6	2.233e-4
PI3K-Akt signaling pathway	KEGG	4	MET, TP53, PIK3CA, JAK3	361	6	22.18	1.148e-5	3.261e-4
Measles	KEGG	3	TP53, PIK3CA, JAK3	139	6	43.20	2.958e-5	7.162e-4
Cellular senescence	KEGG	3	TP53, PIK3CA, TGFBR2	157	6	38.25	4.259e-5	9.636e-4