# GeDiPNet Cluster 424 -- Enriched Pathways -- generated 2026-10-08 09:14:49
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	KEGG	7	PIGM, PIGW, GPAA1, PIGC, PIGH, PIGS, PIGU	30	12	233.53	2.240e-16	8.600e-14
Synthesis of glycosylphosphatidylinositol (GPI)	Reactome	4	PIGM, PIGW, PIGC, PIGH	17	12	235.49	1.350e-9	1.387e-7
Attachment of GPI anchor to uPAR	Reactome	3	GPAA1, PIGS, PIGU	7	12	428.93	2.662e-8	2.026e-6
Metabolic pathways	KEGG	8	PIGM, PIGW, GPAA1, PIGC, GPHN, PIGH, PIGS, PIGU	1563	12	5.12	2.461e-5	7.255e-4
Molybdenum cofactor biosynthesis	Reactome	1	GPHN	6	12	166.81	5.981e-3	5.030e-2
Folate biosynthesis	KEGG	1	GPHN	28	12	35.74	2.763e-2	1.271e-1
GABAergic synapse	KEGG	1	GPHN	89	12	11.25	8.543e-2	2.307e-1
Biosynthesis of cofactors	KEGG	1	GPHN	154	12	6.50	1.435e-1	3.049e-1
Motor proteins	KEGG	1	MYO19	194	12	5.16	1.776e-1	3.435e-1