# GeDiPNet Cluster 419 -- Enriched Pathways -- generated 2026-10-08 04:13:48
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Non-integrin membrane-ECM interactions	Reactome	3	COL3A1, COL1A1, FGF2	24	18	83.40	5.610e-6	2.128e-4
Relaxin signaling pathway	KEGG	4	COL3A1, ACTA2, COL1A1, TGFB1	130	18	20.53	3.566e-5	9.793e-4
Intestinal immune network for IgA production	KEGG	3	CXCL12, CXCR4, TGFB1	50	18	40.03	5.302e-5	1.357e-3
Signaling by ROBO receptors	Reactome	2	CXCL12, CXCR4	12	18	111.20	1.388e-4	2.949e-3
Extracellular matrix organization	Reactome	2	COL3A1, COL1A1	15	18	88.96	2.202e-4	4.252e-3
Syndecan interactions	Reactome	2	FGF2, TGFB1	16	18	83.40	2.514e-4	4.726e-3
AGE-RAGE signaling pathway in diabetic complications	KEGG	3	COL3A1, COL1A1, TGFB1	101	18	19.82	4.298e-4	7.242e-3
Amoebiasis	KEGG	3	COL3A1, COL1A1, TGFB1	103	18	19.43	4.552e-4	7.575e-3
Interleukin-4 and Interleukin-13 signaling	Reactome	3	ALOX5, FGF2, TGFB1	108	18	18.53	5.230e-4	8.418e-3
MET activates PTK2 signaling	Reactome	2	COL3A1, COL1A1	30	18	44.48	9.002e-4	1.282e-2
Biosynthesis of DPAn-3-derived 13-series resolvins	Reactome	1	ALOX5	1	18	667.22	1.499e-3	1.890e-2
Collagen chain trimerization	Reactome	2	COL3A1, COL1A1	44	18	30.33	1.934e-3	2.269e-2
Assembly of collagen fibrils and other multimeric structures	Reactome	2	COL3A1, COL1A1	51	18	26.17	2.590e-3	2.824e-2
ECM proteoglycans	Reactome	2	COL3A1, COL1A1	51	18	26.17	2.590e-3	2.824e-2
Collagen degradation	Reactome	2	COL3A1, COL1A1	52	18	25.66	2.691e-3	2.902e-2