# GeDiPNet Cluster 413 -- Enriched Pathways -- generated 2026-10-07 21:18:28
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Tyrosine metabolism	KEGG	3	ADH1B, ADH1C, TYR	36	68	14.72	1.084e-3	1.442e-2
Ethanol oxidation	Reactome	2	ADH1B, ADH1C	12	68	29.44	2.010e-3	2.288e-2
RHO GTPases activate PKNs	Reactome	2	YWHAZ, RHOA	20	68	17.66	5.619e-3	4.732e-2
Receptor-type tyrosine-protein phosphatases	Reactome	2	PTPRD, PTPRF	20	68	17.66	5.619e-3	4.732e-2
Synaptic adhesion-like molecules	Reactome	2	PTPRD, PTPRF	21	68	16.82	6.188e-3	5.043e-2
PAOs oxidise polyamines to amines	Reactome	1	SMOX	2	68	88.31	1.129e-2	7.367e-2
NOTCH4 Activation and Transmission of Signal to the Nucleus	Reactome	1	YWHAZ	2	68	88.31	1.129e-2	7.367e-2
Adherens junction	KEGG	3	ACP1, PTPRF, RHOA	93	68	5.70	1.568e-2	8.945e-2
Interconversion of polyamines	Reactome	1	SMOX	3	68	58.87	1.689e-2	9.371e-2
RUNX2 regulates osteoblast differentiation	Reactome	1	AR	3	68	58.87	1.689e-2	9.371e-2
Axonal growth stimulation	Reactome	1	RHOA	4	68	44.15	2.246e-2	1.098e-1
SLIT2:ROBO1 increases RHOA activity	Reactome	1	RHOA	4	68	44.15	2.246e-2	1.098e-1
Reuptake of GABA	Reactome	1	SLC6A1	4	68	44.15	2.246e-2	1.098e-1
Deactivation of the beta-catenin transactivating complex	Reactome	2	YWHAZ, TLE1	42	68	8.41	2.351e-2	1.127e-1
Fatty acid degradation	KEGG	2	ADH1B, ADH1C	43	68	8.21	2.457e-2	1.154e-1