# GeDiPNet Cluster 394 -- Enriched Pathways -- generated 2026-10-07 21:11:35
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
phospho-PLA2 pathway	Reactome	1	MAPK1	2	15	400.33	2.496e-3	2.686e-2
GnRH secretion	KEGG	2	MAPK1, KCNJ3	65	15	24.64	2.894e-3	3.002e-2
Acute myeloid leukemia	KEGG	2	MAPK1, RUNX1T1	68	15	23.55	3.163e-3	3.196e-2
HDL clearance	Reactome	1	SCARB1	5	15	160.13	6.230e-3	5.059e-2
Scavenging by Class B Receptors	Reactome	1	SCARB1	5	15	160.13	6.230e-3	5.059e-2
Circadian entrainment	KEGG	2	MAPK1, KCNJ3	97	15	16.51	6.330e-3	5.109e-2
Estrogen-stimulated signaling through PRKCZ	Reactome	1	MAPK1	6	15	133.44	7.472e-3	5.688e-2
Negative feedback regulation of MAPK pathway	Reactome	1	MAPK1	6	15	133.44	7.472e-3	5.688e-2
Suppression of apoptosis	Reactome	1	MAPK1	7	15	114.38	8.712e-3	6.306e-2
Cholinergic synapse	KEGG	2	MAPK1, KCNJ3	115	15	13.92	8.798e-3	6.352e-2
Serotonergic synapse	KEGG	2	MAPK1, KCNJ3	115	15	13.92	8.798e-3	6.352e-2
Glutamatergic synapse	KEGG	2	MAPK1, KCNJ3	116	15	13.80	8.946e-3	6.417e-2
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis	Reactome	1	NCOR2	9	15	88.96	1.119e-2	7.338e-2
Gastrin-CREB signalling pathway via PKC and MAPK	Reactome	1	MAPK1	9	15	88.96	1.119e-2	7.338e-2
MAPK1 (ERK2) activation	Reactome	1	MAPK1	9	15	88.96	1.119e-2	7.338e-2