# GeDiPNet Cluster 391 -- Enriched GO Terms (Biological Process) -- generated 2026-10-08 02:10:08
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:23:04.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
immune response	GO:0006955	114	AIM2, C3, CCL11, CCL2, CCL20, CCL22, CCL24, CCL26, CCL5, CCR2, CCR3, CCR5	543	1333	2.94	2.551e-26	9.276e-23
inflammatory response	GO:0006954	95	ADORA1, ADORA2A, AGER, AIM2, ALOX15, ALOX5, AP3B1, ATRN, BDKRB2, C3, C3AR1, C5	467	1333	2.85	4.748e-21	8.817e-18
cytokine-mediated signaling pathway	GO:0019221	43	CCL2, CCR2, CEBPA, CSF2RB, CSF3, CX3CR1, FER, FOSL1, IFNGR1, IL13RA1, IL16, IL17RD	145	1333	4.16	2.842e-16	2.391e-13
positive regulation of type II interferon production	GO:0032729	29	BCL3, CCR2, CD14, F2RL1, HLA-DPA1, HLA-DPB1, IL12B, IL18, IL18R1, IL1B, IL1R1, IL2	77	1333	5.28	1.933e-14	1.167e-11
positive regulation of inflammatory response	GO:0050729	36	AIM2, CCL24, CCR2, CEBPA, ETS1, HTR2A, IL12B, IL15, IL16, IL18, IL1B, IL1RL1	122	1333	4.14	8.911e-14	4.848e-11
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	GO:0002504	13	HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DQB2, HLA-DRA, HLA-DRB1, HLA-DRB3	15	1333	12.15	1.075e-13	5.782e-11
peptide antigen assembly with MHC class II protein complex	GO:0002503	13	HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DQB2, HLA-DRA, HLA-DRB1, HLA-DRB3	16	1333	11.39	5.356e-13	2.528e-10
cell surface receptor signaling pathway via JAK-STAT	GO:0007259	25	BRD2, CCL2, CCR2, CD40, CSF2RB, ERBB4, IFNGR1, IFNL3, IL12B, IL4, IL6, IL6R	67	1333	5.23	1.562e-12	6.748e-10
keratinization	GO:0031424	26	HRNR, IVL, KAZN, KRT7, KRT81, KRT86, LCE1C, LCE1D, LCE3E, LCE5A, SHARPIN, SPRR2B	73	1333	4.99	1.973e-12	8.360e-10
positive regulation of transcription by RNA polymerase II	GO:0045944	151	ADRB2, AHI1, AP3B1, ARID4B, ARNT, ASXL3, BATF, BCL3, CD28, CD40, CDC5L, CDK12	1208	1333	1.75	4.022e-12	1.612e-9
positive regulation of interleukin-6 production	GO:0032755	30	AGER, CYBA, F2RL1, FCER1G, IL16, IL17A, IL1A, IL1B, IL1RL2, IL33, IL6, IL6R	103	1333	4.08	1.486e-11	5.213e-9
positive regulation of canonical NF-kappaB signal transduction	GO:0043123	48	AKAP13, CARD11, CCR7, CD40, CX3CR1, CYLD, EDN1, EDNRB, F2RL1, FASLG, HLA-DRB1, HMOX1	232	1333	2.90	1.561e-11	5.449e-9
positive regulation of chemokine production	GO:0032722	20	AGER, C5, CHIA, EGR1, F2RL1, HMOX1, IL18, IL1B, IL1RL1, IL33, IL4R, IL6	49	1333	5.72	3.870e-11	1.216e-8
positive regulation of immune response	GO:0050778	18	FCER1G, GPR31, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DQB2, HLA-DRA	40	1333	6.31	5.111e-11	1.560e-8
positive regulation of T cell activation	GO:0050870	19	ADA, CARD11, CCL2, CCR2, CD28, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2	45	1333	5.92	5.855e-11	1.765e-8