# GeDiPNet Cluster 39 -- Enriched GO Terms (Biological Process) -- generated 2026-10-07 13:22:18
# GO term enrichment: Biological Process terms (gene2go, human/tax_id=9606 only), upper-tail hypergeometric test, fold enrichment = (overlap / cluster gene count) / (term gene count / universe size), Benjamini-Hochberg FDR-corrected. Top 15 terms per cluster by q-value. See scripts/build_cluster_go_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:23:06.
GO Term	GO ID	Overlap Genes	Overlap Gene Names	Term Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
DNA repair	GO:0006281	51	ATM, CHEK2, MLH1, MLH3, MSH2, MSH6, MUTYH, PALB2, PMS1, PMS2, RAD51D, POLE	420	126	18.01	5.524e-51	1.208e-46
DNA damage response	GO:0006974	55	ATM, CHEK2, MLH1, MLH3, MSH2, MSH6, MUTYH, PALB2, PMS1, PMS2, RAD51D, APC	577	126	14.14	1.950e-49	3.789e-45
interstrand cross-link repair	GO:0036297	18	RAD51D, FANCM, BRIP1, FAAP100, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI	39	126	68.45	1.299e-29	6.492e-26
double-strand break repair via homologous recombination	GO:0000724	19	ATM, PALB2, RAD51D, ASTE1, BRCA1, BRCA2, ERCC4, RAD51, RAD51C, RFWD3, SLX4, XRCC2	119	126	23.68	3.844e-21	7.307e-18
DNA recombination	GO:0006310	16	PALB2, RAD51D, ASTE1, BRCA1, BRCA2, RAD51, RAD51C, SLX4, XRCC2, MRE11, RAD50, RAD54L	110	126	21.57	2.812e-17	3.026e-14
mismatch repair	GO:0006298	11	MLH1, MLH3, MSH2, MSH6, MUTYH, PMS1, PMS2, EXO1, MSH3, TP73, SETD2	30	126	54.38	4.112e-17	4.294e-14
double-strand break repair	GO:0006302	14	ATM, CHEK2, MSH2, TP53, BRCA1, BRCA2, BRIP1, MAD2L2, VCP, MRE11, NBN, RAD50	87	126	23.87	6.842e-16	5.528e-13
homologous recombination	GO:0035825	7	FANCM, BRCA1, BRIP1, BARD1, MRE11, NBN, RAD50	12	126	86.51	4.123e-13	2.026e-10
reciprocal meiotic recombination	GO:0007131	9	ATM, MLH1, MLH3, RAD51D, RAD51, RAD51C, MRE11, RAD50, RAD54L	33	126	40.45	7.255e-13	3.420e-10
DNA strand resection involved in replication fork processing	GO:0110025	7	ATM, BRCA1, BARD1, MRE11, NBN, RAD50, EXO1	14	126	74.15	1.767e-12	7.668e-10
regulation of cell cycle	GO:0051726	16	ATM, MSH2, RAD51D, RB1, TFDP1, TP53, BRCA1, BARD1, NBN, PTEN, CDK9, CDKN1B	262	126	9.06	2.543e-11	8.425e-9
somatic recombination of immunoglobulin gene segments	GO:0016447	5	MLH1, MSH2, MSH6, PMS2, MSH3	6	126	123.59	7.679e-11	2.250e-8
intrinsic apoptotic signaling pathway in response to DNA damage	GO:0008630	9	ATM, CHEK2, MLH1, MSH2, MSH6, BRCA1, BRCA2, TNF, TP73	54	126	24.72	8.884e-11	2.575e-8
positive regulation of transcription by RNA polymerase II	GO:0045944	30	ATM, EPCAM, RB1, KMT2D, TFDP1, TP53, BRCA1, TNF, PTEN, CDK9, NFKBIZ, SMARCA4	1208	126	3.68	3.148e-10	7.991e-8
telomeric 3' overhang formation	GO:0031860	4	DCLRE1B, MRE11, NBN, RAD50	4	126	148.31	1.971e-9	4.081e-7