# GeDiPNet Cluster 387 -- Enriched Pathways -- generated 2026-10-09 09:49:53
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-09 03:30:08.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Tryptophan catabolism	Reactome	2	KYNU, HAAO	11	83	26.31	2.492e-3	2.680e-2
Defective SLC9A6 causes  X-linked, syndromic mental retardation,, Christianson type (MRXSCH)	Reactome	1	SLC9A6	1	83	144.70	6.911e-3	5.441e-2
Nicotinamide salvaging	Reactome	2	PARP8, RNLS	19	83	15.23	7.476e-3	5.710e-2
FMO oxidises nucleophiles	Reactome	1	FMO2	3	83	48.23	2.059e-2	1.069e-1
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	Reactome	1	APOE	3	83	48.23	2.059e-2	1.069e-1
HHAT G278V abrogates palmitoylation of Hh-Np	Reactome	1	HHAT	4	83	36.17	2.736e-2	1.253e-1
Methionine salvage pathway	Reactome	1	MTAP	4	83	36.17	2.736e-2	1.253e-1
Anchoring of the basal body to the plasma membrane	Reactome	3	ALMS1, MARK4, SCLT1	98	83	4.43	3.027e-2	1.328e-1
Retinoid metabolism and transport	Reactome	2	AGRN, APOE	41	83	7.06	3.251e-2	1.381e-1
Tryptophan metabolism	KEGG	2	KYNU, HAAO	42	83	6.89	3.399e-2	1.416e-1
Electric Transmission Across Gap Junctions	Reactome	1	GJD2	5	83	28.94	3.409e-2	1.418e-1
Chylomicron clearance	Reactome	1	APOE	5	83	28.94	3.409e-2	1.418e-1
Voltage gated Potassium channels	Reactome	2	KCNA6, KCNQ5	43	83	6.73	3.549e-2	1.450e-1
Assembly and cell surface presentation of NMDA receptors	Reactome	1	GRIN2C	6	83	24.12	4.076e-2	1.568e-1
Switching of origins to a post-replicative state	Reactome	1	MCM7	6	83	24.12	4.076e-2	1.568e-1