# GeDiPNet Cluster 38 -- Enriched Pathways -- generated 2026-10-08 00:49:56
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
EPHA-mediated growth cone collapse	Reactome	4	EFNA3, EFNA5, EPHA2, EPHA4	20	223	10.77	4.437e-4	7.423e-3
EPH-Ephrin signaling	Reactome	4	EFNA3, EFNA5, EPHA2, EPHA4	22	223	9.79	6.507e-4	9.992e-3
Collagen chain trimerization	Reactome	5	COL18A1, COL2A1, COL5A1, COL12A1, COL4A1	44	223	6.12	1.271e-3	1.668e-2
Extracellular matrix organization	Reactome	3	COL2A1, COL5A1, COL4A1	15	223	10.77	2.437e-3	2.697e-2
Assembly of collagen fibrils and other multimeric structures	Reactome	5	COL18A1, COL2A1, COL5A1, COL12A1, COL4A1	51	223	5.28	2.475e-3	2.730e-2
Collagen degradation	Reactome	5	COL18A1, COL2A1, COL5A1, COL12A1, COL4A1	52	223	5.18	2.697e-3	2.907e-2
Protein digestion and absorption	KEGG	7	ATP1B1, COL18A1, COL2A1, COL5A1, SLC7A8, COL12A1, COL4A1	103	223	3.66	3.038e-3	3.145e-2
Melanin biosynthesis	Reactome	2	OCA2, TYR	5	223	21.54	3.308e-3	3.343e-2
Protein processing in endoplasmic reticulum	KEGG	9	CRYAA, CRYAB, HSPA1A, HSPA1L, KRTCAP2, NPLOC4, SIL1, WFS1, ERO1B	171	223	2.83	4.633e-3	4.231e-2
HSF1-dependent transactivation	Reactome	3	CRYAB, HSPA1A, HSPA1L	19	223	8.50	4.913e-3	4.407e-2
Cholesterol biosynthesis	Reactome	3	CYP51A1, MVK, LSS	21	223	7.69	6.562e-3	5.367e-2
NCAM1 interactions	Reactome	3	COL2A1, COL5A1, COL4A1	21	223	7.69	6.562e-3	5.367e-2
Signaling by Retinoic Acid	Reactome	3	CPT1A, PPARD, RARB	21	223	7.69	6.562e-3	5.367e-2
FGFR3b ligand binding and activation	Reactome	2	FGF18, FGFR3	7	223	15.39	6.778e-3	5.464e-2
Activation of gene expression by SREBF (SREBP)	Reactome	4	CYP51A1, MVK, SCD, LSS	42	223	5.13	7.455e-3	5.806e-2