# GeDiPNet Cluster 375 -- Enriched Pathways -- generated 2026-10-09 06:31:01
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-09 03:30:08.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Ovarian steroidogenesis	KEGG	3	CYP19A1, PTGS2, CGA	52	7	98.98	2.647e-6	1.078e-4
Regulation of lipolysis in adipocytes	KEGG	2	PTGS2, CGA	59	7	58.16	4.904e-4	7.764e-3
Defective CYP19A1 causes Aromatase excess syndrome (AEXS)	Reactome	1	CYP19A1	1	7	1715.71	5.828e-4	8.871e-3
Biosynthesis of EPA-derived SPMs	Reactome	1	PTGS2	1	7	1715.71	5.828e-4	8.871e-3
Biosynthesis of DPAn-3 SPMs	Reactome	1	PTGS2	1	7	1715.71	5.828e-4	8.871e-3
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives	Reactome	1	PTGS2	2	7	857.86	1.165e-3	1.511e-2
C-type lectin receptor signaling pathway	KEGG	2	PTGS2, NLRP3	105	7	32.68	1.545e-3	1.878e-2
Biosynthesis of DHA-derived SPMs	Reactome	1	PTGS2	3	7	571.90	1.748e-3	2.066e-2
Oxytocin signaling pathway	KEGG	2	PTGS2, TRPM2	154	7	22.28	3.289e-3	3.271e-2
Mineralocorticoid biosynthesis	Reactome	1	CGA	6	7	285.95	3.493e-3	3.413e-2
Estrogen biosynthesis	Reactome	1	CYP19A1	6	7	285.95	3.493e-3	3.413e-2
Synthesis of 15-eicosatetraenoic acid derivatives	Reactome	1	PTGS2	6	7	285.95	3.493e-3	3.413e-2
Thyroxine biosynthesis	Reactome	1	CGA	7	7	245.10	4.074e-3	3.806e-2
NOD-like receptor signaling pathway	KEGG	2	TRPM2, NLRP3	187	7	18.35	4.810e-3	4.266e-2
Reactions specific to the complex N-glycan synthesis pathway	Reactome	1	CGA	10	7	171.57	5.815e-3	4.839e-2