# GeDiPNet Cluster 374 -- Enriched Pathways -- generated 2026-10-10 11:10:49
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-10 03:30:08.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Intraflagellar transport	Reactome	3	IFT140, IFT172, WDR19	54	10	66.72	1.008e-5	3.578e-4
Hedgehog 'off' state	Reactome	3	IFT140, IFT172, WDR19	56	10	64.34	1.126e-5	3.913e-4
VxPx cargo-targeting to cilium	Reactome	2	PKD1, PKD2	21	10	114.38	1.299e-4	2.856e-3
Defective ALG8 causes ALG8-CDG (CDG-1h)	Reactome	1	ALG8	1	10	1201.00	8.326e-4	1.220e-2
N-Glycan biosynthesis	KEGG	2	ALG5, ALG8	55	10	43.67	9.051e-4	1.298e-2
Synthesis of dolichyl-phosphate-glucose	Reactome	1	ALG5	2	10	600.50	1.665e-3	2.073e-2
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	Reactome	1	ALG8	11	10	109.18	9.125e-3	6.705e-2
XBP1(S) activates chaperone genes	Reactome	1	DNAJB11	50	10	24.02	4.088e-2	1.584e-1
Protein processing in endoplasmic reticulum	KEGG	1	DNAJB11	171	10	7.02	1.336e-1	2.969e-1
Metabolic pathways	KEGG	2	ALG5, ALG8	1563	10	1.54	3.809e-1	5.444e-1