# GeDiPNet Cluster 370 -- Enriched Pathways -- generated 2026-10-08 19:31:53
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
ECM-receptor interaction	KEGG	2	FRAS1, FREM2	89	22	12.27	1.139e-2	7.585e-2
Ligand-receptor interactions	Reactome	1	PTCH1	7	22	77.99	1.276e-2	8.117e-2
SLBP independent Processing of Histone Pre-mRNAs	Reactome	1	LSM10	10	22	54.59	1.817e-2	1.006e-1
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	Reactome	1	LSM10	11	22	49.63	1.997e-2	1.057e-1
Aspartate and asparagine metabolism	Reactome	1	ASPA	12	22	45.49	2.177e-2	1.113e-1
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Reactome	1	PERP	14	22	38.99	2.536e-2	1.213e-1
Trafficking of GluR2-containing AMPA receptors	Reactome	1	GRIP1	17	22	32.11	3.071e-2	1.344e-1
G beta:gamma signalling through BTK	Reactome	1	GNB5	18	22	30.33	3.249e-2	1.383e-1
Activation of SMO	Reactome	1	PTCH1	18	22	30.33	3.249e-2	1.383e-1
Prostacyclin signalling through prostacyclin receptor	Reactome	1	GNB5	19	22	28.73	3.426e-2	1.424e-1
G beta:gamma signalling through PLC beta	Reactome	1	GNB5	20	22	27.30	3.603e-2	1.465e-1
G beta:gamma signalling through CDC42	Reactome	1	GNB5	20	22	27.30	3.603e-2	1.465e-1
Presynaptic function of Kainate receptors	Reactome	1	GNB5	21	22	26.00	3.780e-2	1.501e-1
Histidine metabolism	KEGG	1	ASPA	22	22	24.81	3.957e-2	1.537e-1
ADP signalling through P2Y purinoceptor 12	Reactome	1	GNB5	22	22	24.81	3.957e-2	1.537e-1