# GeDiPNet Cluster 360 -- Enriched Pathways -- generated 2026-10-07 03:58:48
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-07 03:30:09.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
2-LTR circle formation	Reactome	2	LIG4, XRCC4	7	32	107.23	1.432e-4	3.000e-3
Non-homologous end-joining	KEGG	2	LIG4, XRCC4	13	32	57.74	5.267e-4	8.285e-3
Glycosaminoglycan biosynthesis - heparan sulfate / heparin	KEGG	2	HS6ST3, XYLT1	24	32	31.28	1.830e-3	2.135e-2
FGFR1c and Klotho ligand binding and activation	Reactome	1	KL	3	32	125.10	7.973e-3	5.956e-2
Cell adhesion molecules	KEGG	3	CNTN1, HLA-B, PTPRD	160	32	7.04	8.671e-3	6.299e-2
Nonhomologous End-Joining (NHEJ)	Reactome	2	LIG4, XRCC4	69	32	10.88	1.444e-2	8.523e-2
Sema4D mediated inhibition of cell attachment and migration	Reactome	1	ARHGAP35	8	32	46.91	2.112e-2	1.060e-1
Endosomal/Vacuolar pathway	Reactome	1	HLA-B	8	32	46.91	2.112e-2	1.060e-1
Activation of the phototransduction cascade	Reactome	1	CNGA1	9	32	41.70	2.373e-2	1.132e-1
Endocytosis	KEGG	3	IQSEC1, HLA-B, PSD4	250	32	4.50	2.835e-2	1.251e-1
The activation of arylsulfatases	Reactome	1	SUMF1	13	32	28.87	3.411e-2	1.388e-1
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	Reactome	1	ARHGAP35	14	32	26.81	3.668e-2	1.445e-1
Phospholipase C-mediated cascade: FGFR1	Reactome	1	KL	16	32	23.46	4.182e-2	1.553e-1
Downstream signaling of activated FGFR1	Reactome	1	KL	18	32	20.85	4.692e-2	1.653e-1
tRNA modification in the nucleus and cytosol	Reactome	1	NSUN2	19	32	19.75	4.946e-2	1.706e-1