# GeDiPNet Cluster 350 -- Enriched Pathways -- generated 2026-10-10 02:58:06
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-10 03:30:08.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Estrogen-stimulated signaling through PRKCZ	Reactome	1	PRKCZ	6	15	133.44	7.472e-3	5.886e-2
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	Reactome	1	GNA11	8	15	100.08	9.951e-3	7.054e-2
Acetylcholine regulates insulin secretion	Reactome	1	GNA11	9	15	88.96	1.119e-2	7.604e-2
Defective EXT2 causes exostoses 2	Reactome	1	HSPG2	14	15	57.19	1.735e-2	9.879e-2
Defective EXT1 causes exostoses 1, TRPS2 and CHDS	Reactome	1	HSPG2	14	15	57.19	1.735e-2	9.879e-2
VEGFR2 mediated cell proliferation	Reactome	1	PRKCZ	14	15	57.19	1.735e-2	9.879e-2
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Reactome	1	PRKCZ	15	15	53.38	1.858e-2	1.026e-1
Defective B4GALT7 causes EDS, progeroid type	Reactome	1	HSPG2	20	15	40.03	2.470e-2	1.209e-1
Defective B3GAT3 causes JDSSDHD	Reactome	1	HSPG2	20	15	40.03	2.470e-2	1.209e-1
Defective B3GALT6 causes EDSP2 and SEMDJL1	Reactome	1	HSPG2	20	15	40.03	2.470e-2	1.209e-1
HS-GAG degradation	Reactome	1	HSPG2	22	15	36.39	2.714e-2	1.271e-1
Downregulation of SMAD2/3:SMAD4 transcriptional activity	Reactome	1	SKI	22	15	36.39	2.714e-2	1.271e-1
Thromboxane signalling through TP receptor	Reactome	1	GNA11	24	15	33.36	2.958e-2	1.329e-1
RHO GTPases Activate NADPH Oxidases	Reactome	1	PRKCZ	24	15	33.36	2.958e-2	1.329e-1
Non-integrin membrane-ECM interactions	Reactome	1	HSPG2	24	15	33.36	2.958e-2	1.329e-1