# GeDiPNet Cluster 34 -- Top Shared Genes -- generated 2026-10-08 07:00:05
# Curated genes (disease_gdp) linked to 2 or more of this cluster's member diseases, most widely shared first. Data as of: 2026-10-08 03:15:01.
Gene	Member Diseases Linked	Cluster Size	Linked Diseases
MTR	7	17	Hematologic disease; Homocystinuria with megaloblastic anemia; Hyperhomocysteinemia; Intracellular cobalamin metabolism disorder; Malnutrition; methylcobalamin deficiency type cblG; Neural tube defects, folate-sensitive
MTRR	7	17	Anencephaly; Aprosencephaly; Homocystinuria with megaloblastic anemia; Hyperhomocysteinemia; Intracellular cobalamin metabolism disorder; methylcobalamin deficiency type cblE; Neural tube defects, folate-sensitive
MTHFR	5	17	Anencephaly; Hematologic disease; Hyperhomocysteinemia; Malnutrition; Neural tube defects, folate-sensitive
ABCD4	4	17	Cobalamin c disease; Intracellular cobalamin metabolism disorder; Methylmalonic acidemia; methylmalonic acidemia with homocystinuria, type cblJ
MMADHC	4	17	Cobalamin c disease; Homocystinuria with megaloblastic anemia; Intracellular cobalamin metabolism disorder; Methylmalonic acidemia
HCFC1	3	17	Cobalamin c disease; Intracellular cobalamin metabolism disorder; Methylmalonic acidemia
LMBRD1	3	17	Cobalamin c disease; Intracellular cobalamin metabolism disorder; Methylmalonic acidemia
MMACHC	3	17	Cobalamin c disease; Intracellular cobalamin metabolism disorder; Methylmalonic acidemia
THAP11	3	17	Intracellular cobalamin metabolism disorder; Methylmalonic acidemia; methylmalonic aciduria and homocystinuria
ZNF143	3	17	Intracellular cobalamin metabolism disorder; Methylmalonic acidemia; methylmalonic aciduria and homocystinuria
CBS	2	17	Hyperhomocysteinemia; Malnutrition
MAN2B1	2	17	Alpha-mannosidosis; Methylmalonic acidemia
MCEE	2	17	Methylmalonic acidemia; methylmalonic acidemia due to methylmalonyl-CoA epimerase deficiency
NUAK2	2	17	Anencephaly; Aprosencephaly
PER3	2	17	Advanced sleep phase syndrome; Homocystinuria with megaloblastic anemia
PRDX1	2	17	Cobalamin c disease; Methylmalonic acidemia
RPGRIP1L	2	17	Anencephaly; Aprosencephaly
TRIM36	2	17	Anencephaly; Aprosencephaly