# GeDiPNet Cluster 337 -- Enriched Pathways -- generated 2026-10-08 01:37:32
# Pathway enrichment: KEGG + Reactome, upper-tail hypergeometric test, Benjamini-Hochberg FDR-corrected. Fold enrichment = (overlap / cluster gene count) / (pathway gene count / universe size). Top 15 pathways per cluster by q-value. See scripts/build_cluster_enrichment.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-08 03:30:07.
Pathway	Source	Overlap Genes	Overlap Gene Names	Pathway Gene Count	Cluster Gene Count	Fold Enrichment	P-value	FDR Q-value
Parathyroid hormone synthesis, secretion and action	KEGG	6	MAFB, VDR, GCM2, CASR, PTH1R, PTH	115	22	28.48	4.451e-8	3.190e-6
PTK6 Regulates Cell Cycle	Reactome	2	CCND1, CDKN1B	6	22	181.97	4.784e-5	1.247e-3
Endocrine and other factor-regulated calcium reabsorption	KEGG	3	VDR, PTH1R, PTH	53	22	30.90	1.178e-4	2.584e-3
Class B/2 (Secretin family receptors)	Reactome	2	PTH1R, PTH	18	22	60.66	4.815e-4	7.916e-3
Rheumatoid arthritis	KEGG	3	PTH, ACP5, IL6	95	22	17.24	6.621e-4	1.014e-2
AGE-RAGE signaling pathway in diabetic complications	KEGG	3	CCND1, CDKN1B, IL6	101	22	16.22	7.915e-4	1.165e-2
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Reactome	2	CCND1, CDKN1B	23	22	47.47	7.917e-4	1.165e-2
Post-translational protein phosphorylation	Reactome	3	MEN1, APOL1, IL6	108	22	15.16	9.616e-4	1.351e-2
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	Reactome	3	MEN1, APOL1, IL6	125	22	13.10	1.467e-3	1.864e-2
RHO GTPases activate IQGAPs	Reactome	2	TUBB4A, MEN1	32	22	34.12	1.537e-3	1.926e-2
ADORA2B mediated anti-inflammatory cytokines production	Reactome	3	PTH1R, PTH, IL6	128	22	12.79	1.570e-3	1.957e-2
FoxO signaling pathway	KEGG	3	CCND1, CDKN1B, IL6	133	22	12.31	1.753e-3	2.116e-2
Measles	KEGG	3	CCND1, CDKN1B, IL6	139	22	11.78	1.989e-3	2.318e-2
African trypanosomiasis	KEGG	2	APOL1, IL6	37	22	29.51	2.052e-3	2.371e-2
Transcriptional Regulation by VENTX	Reactome	2	CCND1, IL6	38	22	28.73	2.164e-3	2.467e-2